Excerpt from The Western Medical Reporter, Vol. 7: A Monthly Epitome of Medical Progress
Pal-para from the Use of Iodide of Potassium. - Two cases of ex tensive cutaneous hemorrhage have recently occurred in the practice of the writer, under circumstances that admit of no doubt as to their mode of origin. One patient was under treatment for syphilis, and the other for rheumatoid arthritis. In both cases the iodide, associated with other med icines, was prescribed in the dose of five grains, four times daily. In both cases an extensive purpuric rash, consisting of spots smaller in circumfer ence than a pea, made its appearance within forty-eight hours. Both patients became alarmed and stopped taking medicine; but a few days later, experiencing no ill effects, and finding that the rash was fading, they resumed the use of the medicine. Again, in both cases, a fresh crap of blotches appeared, and the patients returned to the physican for explan ation and further treatment. In both cases explanation was evaded, and the tincture of iron prescribed. One patient returned for the treatment of his original disease in about ten days, and the other in about three weeks. The former still presented a large number of faded spots. The physi eian, not connecting the appearance of the rash with the use of medicine, again prescribed the iodide, but now in simple solution; and again, an ex tensive rash appeared. The cutaneous hemorrhage was not attended by an appreciable disturbance, local or general. Several attempts have been made to bring the syphilitic patient under the inﬂuence of the medicine, during the past six months, but invariably with the result described. The rheumatoid patient, very properly, took alarm, and put himself under the care of another physician.
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