Veterinary Pharmacology and Therapeutics
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Veterinary Pharmacology and Therapeutics

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Veterinary Pharmacology and Therapeutics, Ninth Edition is the long awaited update of the gold-standard reference on veterinary pharmacology and therapeutics. The field of veterinary pharmacology continues to evolve and expand and this new edition has been revised to reflect changes in the field.
Veterinary Pharmacology and Therapeutics, Ninth Edition is thoroughly revised, updated, and expanded to meet the needs of today s veterinarians, veterinary students, and animal health researchers.
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Product details

  • Hardback | 1544 pages
  • 220.98 x 281.94 x 60.96mm | 3,311.21g
  • Arnes, AI, United States
  • English
  • 9th Edition
  • 0813820618
  • 9780813820613
  • 157,548

Back cover copy

Veterinary Pharmacology and Therapeutics, Ninth Edition is the long awaited update of the gold-standard reference on veterinary pharmacology and therapeutics. The field of veterinary pharmacology continues to evolve and expand and this new edition has been revised to reflect changes in the field. Veterinary Pharmacology and Therapeutics, Ninth Edition is a thoroughly revised, updated, and expanded to meet the needs of today's veterinarians, veterinary students, and animal health researchers.


Veterinary Pharmacology and Therapeutics, Ninth Edition introduces new chapters that allow the reader to look at pharmacological concepts from both a pharmacology and clinical perspective. Chapters have been revamped and revised to reflect the current state of the field, and the editors have invited contributors from around the world to provide truly global coverage of the topic.




Veterinary Pharmacology and Therapeutics, Ninth Edition will maintain its place as the indispensible resource on veterinary pharmacology and therapeutics being used today.
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Table of contents

Contributors ix
Preface xv
Section 1. Principles of Pharmacology 3
1. Veterinary Pharmacology: An Introduction to the Discipline 5 Jim E. Riviere and Mark G. Papich
2. Absorption, Distribution, Metabolism, and Elimination 11 Jim E. Riviere
3. Pharmacokinetics 47Jim E. Riviere
4. Mechanisms of Drug Action and Pharmacokinetics/Pharmacodynamics Integration in Dosage Regimen Optimization for Veterinary Medicine 75Pierre-Louis Toutain
Section 2. Drugs Acting on the Autonomic Nervous System 99
5. Introduction to Neurohumoral Transmission and the Autonomic Nervous System 101H. Richard Adams.
6. Adrenergic Agonists and Antagonists 125H. Richard Adams.
7. Cholinergic Pharmacology: Autonomic Drugs 157H. Richard Adams
Section 3. Anesthetics and Analgesics 181
8. Introduction to Drugs Acting on the Central Nervous System and Principles of Anesthesiology 183 Peter J. Pascoe and Eugene P. Steffey
9. Neuromuscular Blocking Agents 211H. Richard Adams
10. Inhalation Anesthetics 229 Eugene P. Steffey
11. Injectable Anesthetic Agents 265 Lysa P. Posner and Patrick Burns
12. Opioid Analgesic Drugs 301 Butch KuKanich and Mark G. Papich
13. Sedative Agents: Tranquilizers, Alpha-2 Agonists, and Related Agents 337 Lysa P. Posner and Patrick Burns
14. Local Anesthetics 381 Alistair I. Webb and Luisito S. Pablo
15. Euthanizing Agents 401 Alistair I. Webb
Section 4. Autacoids and Anti-inflammatory Drugs 409
16. Histamine, Serotonin, and Their Antagonists 411 H. Richard Adams
17. Peptides: Angiotensin and Kinins 429H. Richard Adams
18. Prostaglandins, Related Factors, and Cytokines 439H. Richard Adams
19. Analgesic, Anti-inflammatory, Antipyretic Drugs 457 Peter Lees
20. Anticonvulsant Drugs 493Mark G. Papich
21. Drugs Affecting Animal Behavior 509Barbara L. Sherman and Mark G. Papich
Section 5. Drugs Acting on the Cardiovascular System 539
22. Digitalis, Positive Inotropes, and Vasodilators 541Matthew W. Miller and H. Richard Adams
23. Antiarrhythmic Agents 575 Matthew W. Miller and H. Richard Adams
Section 6. Drugs Affecting Renal Function and Fluid-Electrolyte Balance 603
24. Principles of Acid-Base Balance: Fluid and Electrolyte Therapy 605Deborah T. Kochevar and Maya M. Scott
25. Diuretics 647 Deborah T. Kochevar
Section 7. Drugs Acting on Blood and Blood Elements 671
26. Hemostatic and Anticoagulant Drugs 673H. Richard Adams
Section 8. Endocrine Pharmacology 691
27. Hypothalamic and Pituitary Hormones 693Srujana Rayalam, Margarethe Hoenig, and Duncan Ferguson
28. Hormones Affecting Reproduction 717Doodipla S. Reddy and John E. Gadsby
29. Thyroid Hormones and Antithyroid Drugs 735 Duncan C. Ferguson
30. Glucocorticoids, Mineralocorticoids, and Adrenolytic Drugs 771 Duncan C. Ferguson, Levent Dirikolu, and Margarethe Hoenig
31. Drugs Influencing Glucose Metabolism 803Margarethe Hoenig
Section 9. Chemotherapy of Microbial Diseases 817
32. Antiseptics and Disinfectants 819 Mark C. Heit and Jim E. Riviere
33. Sulfonamides and Potentiated Sulfonamides 835 Mark G. Papich and Jim E. Riviere
34. -Lactam Antibiotics: Penicillins, Cephalosporins, and Related Drugs 865Mark G. Papich and Jim E. Riviere
35. Tetracycline Antibiotics 895 Mark G. Papich and Jim E. Riviere
36. Aminoglycoside Antibiotics 915 Mark G. Papich and Jim E. Riviere
37. Chloramphenicol and Derivatives, Macrolides, Lincosamides, and Miscellaneous Antimicrobials 945 Mark G. Papich and Jim E. Riviere
38. Fluoroquinolone Antimicrobial Drugs 983Mark G. Papich and Jim E. Riviere
39. Antifungal and Antiviral Drugs 1013Jennifer L. Davis, Mark G. Papich, and Mark C. Heit
Section 10. Chemotherapy of Parasitic Diseases 1051
40. Antinematodal Drugs 1053 Carlos E. Lanusse, Luis I. Alvarez, Juan M. Sallovitz, Maria L. Mottier, and Sergio F. Sanchez Bruni
41. Anticestodal and Antitrematodal Drugs 1095Carlos E. Lanusse, Guillermo L. Virkel, and Luis I. Alvarez
42. Macrocyclic Lactones: Endectocide Compounds 1119Carlos E. Lanusse, Adrian L. Lifschitz, and Fernanda A. Imperiale
43. Antiprotozoan Drugs 1145 Jennifer L. Davis and Jody L. Gookin
44. Ectoparasiticides 1181 Ronald E. Baynes
Section 11. Specialty Areas of Pharmacology 1203
45. Chemotherapy of Neoplastic Diseases 1205Gordon L. Coppoc
46. Immunosuppressive Drugs and Cyclosporine 1233 Mark G. Papich
47. Drugs Affecting Gastrointestinal Function 1247Mark G. Papich
48. Dermatopharmacology: Drugs Acting Locally on the Skin 1273 Jim E. Riviere
49. Drugs that Affect the Respiratory System 1295Mark G. Papich
50. Pharmacogenomics 1313 Katrina L. Mealey
51. Therapeutic Drug Monitoring 1323Mark G. Papich
52. Considerations for Treating Minor Food-Producing Animals with Veterinary Pharmaceuticals 1331 Lisa A. Tell, Margaret Oeller, and Arthur L. Craigmill
53. Zoological Pharmacology 1343Robert P. Hunter
Section 12. Regulatory Considerations. 1353
54. Legal Control of Veterinary Drugs 1355Stephen F. Sundlof
55. Drug Approval Process 1365 Marilyn Martinez, Melanie Berson, Bernadette Dunham, Joan Gotthardt, and Laura Hungerford
56. Veterinary Pharmacy 1407 Gigi Davidson
57. Regulation of Drug and Medication Use in Performance Animals 1419 Cynthia A. Cole and Keith Zientek
58. Adverse Drug Reactions 1431 Victoria Hampshire and Margarita A. Brown
59. Dosage Forms and Veterinary Feed Directives 1439 Jim E. Riviere and Geof W. Smith
60. USP s Role in Veterinary Pharmacology and Evidence-Based Information 1445Cory Langston, Stefan Schuber, and Ian R. DeVeau
61. Chemical Residues in Tissues of Food Animals 1453Jim E. Riviere and Stephen F. Sundlof
Index 1463
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About Mark G. Papich

Jim E. Riviere, DVM, PhD, DSc (hon), ATS, is Distinguished Professor and Director for the Center for Chemical Toxicology Research and Pharmacokinetics with the Department of Population Health and Pathobiology, College of Veterinary Medicine at North Carolina State University. He is also Editor for the Journal of Veterinary Pharmacology and Therapeutics.

Mark G. Papich, DVM, MS, Diplomate ACVCP,is Professor of Clinical Pharmacology, Department of Molecular Biomedical Sciences, College of Veterinary Medicine at North Carolina State University.
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