Veterinary Extension Quarterly Volume 1-71

Veterinary Extension Quarterly Volume 1-71

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This historic book may have numerous typos and missing text. Purchasers can usually download a free scanned copy of the original book (without typos) from the publisher. Not indexed. Not illustrated. 1921 edition. Excerpt: ...is passed through a large number of rabbits a so-called "fixed virus" is obtained, which no longer produces typical inclusions but causes a typical Negri, lyssa or passage bodies. Nevertheless, the disease produced with this fixed virus shows its usual character and the virus remains a rabies virus. It is also of significance to mention that Negri bodies do not develop in nerve cells, resistant by means of immunization. The relation between smallpox and vaccinia is still more interesting. Smallpox virus passed through calves becomes vaccine virus and remains vaccine virus even after reinoculation into human beings. Furthermore, vaccine virus is changed in such a way that a different disease is caused by its action. Likewise the intracellular pathology is changed because in cells affected by smallpox, inclusions are seen in the nucleus as well as in the cytoplasm, while in cells injured by vaccinia inclusions are found only in the cytoplasm. We do not know what these changes mean, but we are safe in regarding them as an indication of the close relationship which, after all, must exist between some viruses and their corresponding inclusion bodies. Finally, a few words must be said about the relationship of inflammation, proliferation and degeneration to the formation of inclusion bodies. If the inclusion bodies in various virus diseases possess an etiological significance it is logical to think that they would be found mainly and most numerously in areas in which the inflammatory lesions are most pronounced. In Borna disease of horses, Ioest, Zwick and Seifried and Bemann in our laboratories have definitely shown that the occurrence of inclusion bodies is not dependent upon the degree and localization of the inflammatory...show more

Product details

  • Paperback | 254 pages
  • 189 x 246 x 13mm | 458g
  • Rarebooksclub.com
  • United States
  • English
  • black & white illustrations
  • 1236797280
  • 9781236797285