The Venom of Heloderma

The Venom of Heloderma

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This historic book may have numerous typos and missing text. Purchasers can download a free scanned copy of the original book (without typos) from the publisher. Not indexed. Not illustrated. 1913 edition. Excerpt: ... sodium-chloride solution, to which venom had been added in the proportion of 20 or 30 mg. to every 800 c.c. of the sodium-chloride solution. Quantities of urine secreted during the inflow of every 50 or 100 c.c. of the NaCl solution were noted. At the end of the experiment, after the inflow of fluid had been stopped, the animal was killed and the quantity of fluid in the peritoneal cavity and small intestines was measured. By means of a mercury manometer connected with the carotid artery of the rabbit, the arterial bloodpressure was measured during the time of the infusion. Immediately after the infusion of the venom-sodium-chloride solution was started the blood-pressure of the rabbit became rapidly lower; after 20 to 50 c.c. had been infused, a fall of 10 to 40 mm. of mercury could be observed; in our 5 cases the average fall of blood-pressure was 24 mm. After the first rapid fall the blood-pressure remained either approximately stationary or gradually decreased slightly. After 600 or 700 c.c. of the venom-sodium-chloride mixture had been infused the arterial blood-pressure was usually between 80 and 60 mm. of mercury (figs. 15 and 16). In only one of these experiments, toward the end of the infusion, the blood-pressure fell below 50 mm. In this experiment, the only one in which 30 mg. of venom was used, the animal died as a Van Denburgh nnd Wight, Trans. Amer. Phil. Soc., 1898, xix, 199. result of the fall of blood-pressure (see fig. 17). In all other experiments the animals were alive at the end of the experiment. During the time of infusion a large quantity of urine, an average of 590 c.c. for 1,000 c.c. of infused fluid, was secreted. In no case was any ascitic fluid found at the expiration of the experiments, notwithstanding the fact that...show more

Product details

  • Paperback | 88 pages
  • 189 x 246 x 5mm | 172g
  • Rarebooksclub.com
  • Miami Fl, United States
  • English
  • black & white illustrations
  • 1236551346
  • 9781236551344