The Vascular Smooth Muscle Cell

The Vascular Smooth Muscle Cell : Molecular and Biological Responses to the Extracellular Matrix

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In the last several years, the development of reagents that recognize smooth muscle-specific proteins has enabled researchers to identify smooth muscle cells (SMC) in tissue undergoing both differentiation and repair. These developments have led to increased research on SMC. The latest volume in the Biology of the Extracellular Matrix Series takes a current and all-encompassing look at this growing area of research. Devoted entirely to the subject of SMC, the book covers a diversity of topics-from SMC architecture and contractility to differentiation and gene expression in development. It also examines the proliferation and replication of SMC and its role in pharmacology and vascular disease. A must for cell, developmental, and molecular biologists, this book also will appeal to cardiologists, pathologists, and biomedical researchers interested in smooth muscle cells.
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Product details

  • Hardback | 416 pages
  • 157.7 x 235.5 x 23.9mm | 776.33g
  • Academic Press Inc
  • San Diego, United States
  • English
  • illustrations, index
  • 0126323100
  • 9780126323108

Table of contents

Overview - development of the vessel wall, G.R. Campbell and J.H. Campbell; smooth muscle cell differentiation during early development and during intimal thickening formation of the ductus arteriosus, A.C. Gittenberger-De Groot, et al; integrins, cytoskeletal and extracellular matrix proteins in developing smooth muscle cells of human aorta, M.A. Glukhova, et al; relevance of smooth muscle replication and development to vascular disease, S.M. Schwartz, et al; smooth muscle gene expression during developmental maturation, G. Liau and D.K.M. Han; overview - molecular identification smooth muscle cells, G.K. Owens; architecture of the smooth muscle cell, J. Victor Small and A.J. North; molecular basis of smooth muscle contractility - myosin heavy chains - gene structure and expression, M. Periasamy and R. Nagai; vascular smooth muscle-specific gene expression, T.C. McQuinn and R.J. Schwartz; overview - molecular controls of smooth muscle hypertrophy and hyperplasia, R. Ross; overview - smmoth muscle cell function from the clinical perspective, A.W. Clowes; regulation of arterial smooth muscle growth, M.A. Riedy; pharmacology of smooth muscle cell proliferation, C.L. Jackson; smooth muscle cell and fibroblast biological and functional features - similarities and differences, A. Desmouliere and G. Gabbiani; smooth muscle cell proliferation in hypertension - possible muscle cell proliferation in hypertension - possible contribution to arterial remodelling, J.G.R. De May.
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