University of California Publications in Physiology Volume 1

University of California Publications in Physiology Volume 1

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This historic book may have numerous typos and missing text. Purchasers can download a free scanned copy of the original book (without typos) from the publisher. Not indexed. Not illustrated. 1903 edition. Excerpt: ...but also an increased secretion of fluid into the intestine. This was found to be true not only when the purgatives were administered subcutaneously or intravenously, but also when the saline solutions were applied locally to the peritoneal surfaces of the intestine. It was shown that the administration of solutions of calcium chloride by any of these methods counteracts the effect of the purgative salts; and it was further pointed out that these actions are analogous to the production and suppression of twitchings in voluntary muscle described by Loeb." The following is a description of a number of experiments made on loops of the intestine entirely removed from the body in order to determine the action of the saline solutions on the isolated intestine, more particularly with regard to the production of increased secretion of fluid into the intestine. 1 MacCallum, J. B.; University of California Publications, Physiology. ItKW. i. p. 5. American Journal of Physiology. 1903, x, p. 101, and 1904, x, p. 259.-Loeb, J.; Festschrift filr Fick 1899; Arohiv filr die gesamnite Physiologic, 1902. xci, p. 248. Methods. In these experiments only rabbits were made use of. Morphine was employed as an anaesthetic, 4-5 c.c. 1% solution of the hydrochlorate being administered. The abdominal cavity was opened and the blood vessels supplying the loop selected were carefully tied off. Two pairs of ligatures were then placed around the intestine so that the loop was properly isolated. The intestine was then cut between each pair of ligatures and the mesentery divided between the blood vessel ligatures and the intestine. In this way the loop could be taken from the body without injuring it, and without causing the animal to lose more than a few drops of more

Product details

  • Paperback | 64 pages
  • 189 x 246 x 3mm | 132g
  • Miami Fl, United States
  • English
  • black & white illustrations
  • 123654787X
  • 9781236547873