Treatment Resistant Depression

Treatment Resistant Depression : A Roadmap for Effective Care

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As many as 35-40% of patients afflicted with Major Depressive Disorder (MDD) are treatment resistant, a situation that places a massive emotional and financial burden on society and challenges the mental health profession to develop new treatment paradigms and practices. Even the most astute clinicians can be frustrated when treatment options fail to be effective or work for only a brief time, leaving them to wonder what course to pursue next. Treatment Resistant Depression: A Roadmap for Effective Care gives clinicians and their patients what they need most desperately: a sequence of steps that reflect state-of-the-art diagnostic procedures and integrates all evidence-based treatment modalities -- in short, a roadmap to wellness and recovery.Based primarily on the experiences of the authors, all of whom are leading researchers and/or clinicians in Treatment Resistant Depression and affiliated with the University of Michigan Comprehensive Depression Center, the book also draws upon the clinical research advances and treatment innovations of programs around the world. Although the book's step-by-step organization is clear and easy to follow, its coverage, scope, and level of sophistication are anything but simplified. This book  Is comprehensive, addressing treatment options, including psychopharmacotherapy, psychotherapy, neuromodulation (ECT, transcranial magnetic stimulation, deep brain stimulation, vagus nerve stimulation), exercise, nutrition, self-management approaches to enhance adherence, behavioral sleep programs, and others Addresses treatment resistant depression across the lifespan, reflecting the diverse demographics of depression, which knows no age, gender, or socioeconomic status Emphasizes the authors' commitment to early intervention and provides techniques for identifying young people who are at risk for developing depression or already expressing symptoms of the disease Recognizes the chronicity of depression, rather than focusing on only the acute stage, and in this way allows for more effective treatment over the patient's lifetime Introduces self-management as playing a critical role in the patient's prognosis, engagement, adherence to clinical steps that help maintain recovery, and self-esteem Promotes the development of new, personalized, and predictive biomarkers to target treatment more effectively. Designed to be useful across disciplines and treatment modalities, the book includes a multitude of tables, graphs, and learning aids that will benefit students, instructors, and clinicians. At the same time, the book promises to be a valuable resource for patients and their families, since Treatment Resistant Depression is both difficult to live with and little understood. No other book offers so much practical guidance, sound research and more

Product details

  • Paperback | 364 pages
  • 152.4 x 226.06 x 25.4mm | 612.35g
  • American Psychiatric Association Publishing
  • VA, United States
  • English
  • 12 Line drawings, unspecified; 17 Tables, unspecified
  • 1585624098
  • 9781585624096
  • 807,487

Review quote

"Dr. Greden and colleagues have written a road map for treatment resistant depression that has immediate appeal for the general practitioner and mood specialist alike. The case vignettes with evidenced based reviews and clinical pearls in mood disorders with emphasis on areas often underdeveloped (young adults, dual diagnosis, late life) make "Treatment Resistant Depression: A Roadmap for Effective Care" a great resource for my practice and my patients."-- "Mark A. Frye, M.D., Professor of Psychiatry, Director, Integrated Mood Group, Mayo Clinic, Department of Psychiatry "show more

Flap copy

This unique book presents the treatment "roadmap" implemented by the University of Michigan Comprehensive Depression Center's Treatment Resistant Depression Program, step-by-step guidance that has long eluded clinicians, patients, and their families. Writing across discipline, modality, lifespan, and patient demographics, the authors have compiled the most current thinking on TRD and distilled it into a highly readable, imminently practical, and brilliantly organized source of hope. The authors believe that early intervention is critical, and they advocate strategies for renewed focus on identifying youths who are at risk or already symptomatic. Similarly, they devote chapters to special populations such as pregnant women, older people, and those with comorbidities. Perhaps most useful to patients and their families, the book has a strong self-care orientation, emphasizing the importance of exercise, nutrition, and healthy sleep guidelines. Patients who are actively engaged in managing their disease often have better outcomes. Treatment Resistant Depression is frequently a lifetime diagnosis. The book acknowledges that fact and offers a systematic course of treatment grounded in evidence-based research that is current and comprehensive. Treatment Resistant Depression: A Roadmap for Effective Care offers a new way of conceptualizing an old enemy, and should prove to be an indispensable weapon in the more

About University of Michigan Comprehensive Depression Center

John F. Greden, M.D., is Rachel Upjohn Professor of Psychiatry and Clinical Neurosciences, University of Michigan; Executive Director, University of Michigan Comprehensive Depression Center; Research Professor, Molecular and Behavioral Neurosciences Institute; and Chair, National Network of Depression Centers.Michelle B. Riba, M.D., M.S., is Clinical Professor; Associate Director, Michigan Institute for Clinical and Health Research; Associate Director, University of Michigan Comprehensive Depression Center; Associate Chair for Integrated Medical and Psychiatric Services, University of Michigan, and Past President, American Psychiatric Association.Melvin G. McInnis, M.D., is Thomas B. and Nancy Upjohn Woodworth Professor of Bipolar Disorder and Depression; Professor of Psychiatry; Associate Director, University of Michigan Comprehensive Depression Center; and Section Director, Depression Center, University of more

Table of contents

ContributorsDisclosure of InterestsForewordPrefaceDedication and AcknowledgementsChapter 1. Treatment resistant depression: overview of the University of Michigan Depression Center roadmapChapter 2. Psychopharmacological roadmap for treatment resistant depressionChapter 3. Treatment resistant depression in adolescentsChapter 4. Recognizing and treating depression and bipolar disorder on college campuses: early identification and interventionChapter 5. Treatment resistant depression in pregnant womenChapter 6. Treatment resistant depression in later lifeChapter 7. Treatment resistant depression and comorbid medical problems: Cardiovascular disease nd cancerChapter 8. Alcohol and drug use: Contributions to treatment resistance for patients with depressionChapter 9. Sleep and circadian rhythms: A understudied area in treatment resistant depressionChapter 10. Psychotherapy strategies for treatment resistant depressionChapter 11. Device-related neuromodulation in treatment resistant depressionChapter 12. Exercise, nutrition, and treatment resistant depressionChapter 13. The bipolar disorder medical care model: A collaborative approach for reducing disparities in medical care among patients with bipolar disorderChapter 14. Expanding services for patients with treatment resistant depression: The role of peer supportChapter 15. Genetics of mood disorders: general principles and potential applications for treatment resistant depressionIndexshow more

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