Transplant-Associated Coronary Artery Vasculopathy

Transplant-Associated Coronary Artery Vasculopathy

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Heart transplants often result in the development of an accelerated form of coronary arterial disease, recent studies of which are presented here in ten chapters by specialists in the US, UK, and Canada. Topics include: atherosclerosis as a response to injury; the immune response to endothelial cells; the role of hemostasis, anticoagulation, fibrinolysis and endothelial activation; nonimmune factors in the etiology of graft coronary arteriosclerosis; tissue remodeling and extracellular matrix proteins; findings from animal experiments on the pathogenesis of transplant arteriopathy; cytomegalovirus as a contributing factor; lipids and lipid lowering therapy; and immunosuppressive drugs. Rose is affiliated with the Imperial College School of Medicine in Harefield, Middlesex, UK. Annotation c. Book News, Inc., Portland, OR ( more

Product details

  • Hardback | 204 pages
  • 157.5 x 236.2 x 20.3mm | 544.32g
  • Landes Bioscience
  • Texas, United States
  • English
  • 50 black & white illustrations, 27 black & white tables
  • 1587060051
  • 9781587060052

Table of contents

Coronary Arterial Disease in the Cardiac Allograft. Atherosclerosis: Response to Injury. The Immune Response to Endothelial Cells. Role of Hemostasis, Anticoagulation, Fibrinolysis and Endothelial Activation. Nonimmune Factors in the Etiology of Graft Coronary Arteriosclerosis. Tissue Remodeling and Extracellular Matrix Proteins Insights Regarding the Pathogenesis of Transplant Arteriopathy from Experiments with Animals. Cytomegalovirus as a Contributing Factor in Transplant Vascular Sclerosis. Lipids and Lipid Lowering Therapy. Immunosuppressive Drugs for the Prevention and Treatment of Transplant Coronary Artery more