Translating Epigenetics to the Clinic

Translating Epigenetics to the Clinic

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Description

Translating Epigenetics to the Clinic reviews current methodological tools and experimental approaches used by leading translational researchers seeking to use epigenetics as a clinical model. It organizes epigenetics into disease treatment areas with a major focus on oncology, and with much coverage of pervasive treatment categories such as diabetes, as well as the `diseases of modernity'-including pharmacological addiction, dementia, and ageing.

Pedagogically, the work concentrates on the latest knowledge, laboratory techniques, and experimental approaches used by translational research leaders in this field. The book promotes cross-disciplinary communication between the sub-specialties of medicine. In common with the rest of the books in Translational Medicine, the book remains unified in theme by emphasizing recent innovations, critical barriers to progress, and the new tools being used to overcome them. Also includes specific areas of research that require additional study to advance the field as a whole.
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Product details

  • Hardback | 324 pages
  • 152 x 229 x 19.05mm | 700g
  • Academic Press Inc
  • San Diego, United States
  • English
  • black & white illustrations
  • 0128008024
  • 9780128008027

Table of contents

1. Introduction (TBA)
2. Epigenetics and muscle function in COPD (Esther Barreiro, M.D., Ph.D.)
3. Epigenetics of pulmonary fibrosis (David Schwartz, MD; Ivana Yang, PhD)
4. Epigenetics in acute kidney injury and renal cancer (Gregory Dressler, Ph.D.)
5. Epigenetic mechanisms of carcinogenesis (Max Costa, Ph.D.)
6. Epigenetics of epithelial-to-mesenchymal-transition in breast cancer (Sonja C. Stadler, PhD)
7. Maria E. Figueroa, M.D. (Epigenetics of leukemia)
8. Epigenetics of diabetes (Carmella Evans-Molina, MD, PhD)
9. Epigenetic control of fetal hemoglobin (Gordon D. Ginder, MD)
10. Nucleosome remodeling and deacetylase (NuRD) complex in development and disease (Michael Rauchman, MD)
11. RNA epigenetics (Tao Pan, PhD)
12. Epigenetics in immune-related diseases (Xiao-Feng Yang, MD, PhD, FAHA)
13. Epigenetics of dementia in aging (David A. Bennett, MD)
14. Epigenetics of aging (TBA)
15. Epigenetics of stem cell reprogramming (TBA)
16. Epigenetics in cardiovascular disease (TBA)
17. Epigenetics and nutrition (TBA)
18. Epigenetic effects of drug use (TBA)
19. Epigenetics of inflammation (TBA)
20. Epigenetics of lung cancer (TBA)
21. Epigenetics and mitochondria (TBA)
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Review Text

"In a very innovative way, the authors start the exploration of the concept of epigenetic medicine as interventions to treat epigenetic disorders. Although epigenetics is the subject of multiple books currently, very few provide a link between causation, pathology, and intervention. These authors touch on the beginning of a new field in genomic medicine, which should be the subject of many publications in the future." --Doody's Review
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Review quote

"In a very innovative way, the authors start the exploration of the concept of epigenetic medicine as interventions to treat epigenetic disorders. Although epigenetics is the subject of multiple books currently, very few provide a link between causation, pathology, and intervention. These authors touch on the beginning of a new field in genomic medicine, which should be the subject of many publications in the future." --Doody's Review
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About Jeffrey Laurence

Dr Laurence is pursuing the pathophysiology of cardiovascular and skeletal abnormalities linked to HIV disease and its therapies at Weill Cornell. Dr Laurence is the editor-in-chief of Translational Medicine, which Elsevier co-publishes with the CSCTR.
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