Transfusion Medicine and Hemostasis

Transfusion Medicine and Hemostasis : Clinical and Laboratory Aspects

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Description

Transfusion Medicine and Hemostasis is a manual-style book that links transfusion medicine and hemostasis to laboratory methods and diagnostic tests engaged in routine and specialized coagulation laboratories. The book is divided into two main parts with chapters that are brief and readable.
The first main part of the book is subdivided into blood banking and transfusion medicine. Under blood banking, the chapters cover blood collection, donation process, component manufacturing, donor testing and storage; transfusion-medicine chapters examine the components for transfusion, pre-transfusion immunohematology testing, blood groups, blood products and their modifications, approaches to transfusion therapy in specific clinical settings, and transfusion reactions and complications. In addition, chapters that talk about apheresis, cellular therapy, and tissue banking in the hospital setting are included.
Hemostasis, the second main part of the book, is subdivided into three sections. The first section, clinical coagulation, includes chapters about neonatal thrombocytopenia, inherited platelet function disorders, immune thrombocytopenia, immune-mediated coagulopathies, congenital bleeding disorders, and acquired bleeding disorders. The second section relates to laboratory testing of coagulation, with chapters about laboratory assessments of platelet disorders, von Willebrand disease, coagulation factor disorders, fibrinogen and fibrinolysis, tests for hypercoagulable state and for activation of the coagulation system, and laboratory support for anticoagulation. The third section discusses coagulation factor products.
This book will be valuable for the education of trainees, practitioners, and future leaders in these fields.
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Product details

  • Paperback | 775 pages
  • 180.34 x 236.22 x 33.02mm | 997.9g
  • United States
  • English
  • 0123744326
  • 9780123744326
  • 754,523

Table of contents

I. BLOOD BANKING AND TRANSFUSION MEDICINE
Introduction of blood banking and transfusion medicine
A. Blood Donors and Donor Centers
Donation process
Component preparation and storage
Donor testing
Quality management from the donor center perspective

B. Hospital Transfusion Service
Pretransfusion testing
Blood group antigens and antibodies
Blood components
Special products and processes
Specific clinical settings
Transfusion reactions
Therapeutic apheresis
HPC cell collection and processing
Tissue banking
Quality management from the transfusion service perspective

II. COAGULATION
A. Overview of the coagulation system
Generalized patient approach
Neonatal thrombocytopenia
Inherited platelet function disorders
Immune thrombocytopenia
Immune mediated coagulopathies
Bleeding disorders
Acquired bleeding disorders

B. Laboratory testing of coagulation
General screening tests
Laboratory assessment of platelet function
Laboratory diagnosis of qualitative platelet disorders
Laboratory diagnosis of quantitative platelet disorders
Von Willebrand Disease
Laboratory assessment of presence and function of coagulation factors
Fibrinogen and fibrinolysis
Genetic tests for hypercoagulable state
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Review Text

"Given the cross disciplinary nature of transfusion medicine and the intensive focus on transfusion medicine and hemostasis as evidenced by the Transfusion Medicine, Hemostasis Clinical Trials Network sponsored by NHLBI, this textbook is both timely and needed by practitioners in both clinical and laboratory disciplines. The book is written exclusively by faculty of one of the leading programs in transfusion medicine, hemostasis, and hematology and covers important adult and pediatric concepts in these two fields. I know that hematologists, pathologists, and clinicians who depend upon transfusion and hemostatic support will find this novel text interesting and valuable in their practice and teaching efforts."

--Paul M. Ness, MD, Director, Transfusion Medicine, Johns Hopkins Medical Institutions, Professor of Pathology and Medicine & Oncology, Johns Hopkins University, Baltimore, MD, USA

"Few transfusion medicine texts have given such weight and focus to hemostasis. The combination of clinical and laboratory aspects in a concise format is superb. This book will be very useful both for those interested in transfusion medicine and those interested in hemostasis."

-- Ellis Neufeld, MD, PhD, Associate Chief, Division of Hematology/Oncology , Children's Hospital Boston, Associate Professor, Department of Pediatrics, Harvard Medical School, Boston, MA, USA

"This is an outstanding addition to transfusion medicine textbooks. For years we have needed the optimal text for training residents, fellows, and practitioners all in one book. The inclusion of coagulation, laboratory aspects and transfusion medicine was insightful and reflects the multi-disciplinary and clinical identity of Transfusion Medicine."

--Leslie Silberstein, MD, Director, Joint Program in Transfusion Medicine at Children's Hospital Boston, Dana-Farber Cancer Institute, and Brigham and Women's Hospital, Professor of Pathology, Harvard Medical School, Boston, MA, USA

"The book edited by Dr. Christopher Hillyer, Beth Shaz, James Zimring and Thomas Abshire entitled Transfusion Medicine and Hemostasis: Clinical and Laboratory Aspects provides wonderful bite-size comments and clear concise recommendations. This makes for a very practical textbook that should be useful to a wide body of healthcare workers who deal with the use of blood products or patients with bleeding or thrombosis. The coverage of topics in transfusion medicine and coagulation is broad. This is a major advantage of the textbook that makes it particularly useful. The connection between the underlying pathophysiology and the clinical disorders and the treatment recommendations is at the level of just what you want to know. This book is a winner, and I strongly endorse its use by anyone requiring information in this field."

--Michael Laposata, MD, PhD, Pathologist in Chief, Vanderbilt University Hospital, Professor of Pathology and Medicine, Vanderbilt University, Nashville, TN, USA
"Given the cross disciplinary nature of transfusion medicine and the intensive focus on transfusion medicine and hemostasis as evidenced by the Transfusion Medicine, Hemostasis Clinical Trials Network sponsored by NHLBI, this textbook is both timely and needed by practitioners in both clinical and laboratory disciplines. The book is written exclusively by faculty of one of the leading programs in transfusion medicine, hemostasis, and hematology and covers important adult and pediatric concepts in these two fields. I know that hematologists, pathologists, and clinicians who depend upon transfusion and hemostatic support will find this novel text interesting and valuable in their practice and teaching efforts."

--Paul M. Ness, MD, Director, Transfusion Medicine, Johns Hopkins Medical Institutions, Professor of Pathology and Medicine & Oncology, Johns Hopkins University, Baltimore, MD, USA

"Few transfusion medicine texts have given such weight and focus to hemostasis. The combination of clinical and laboratory aspects in a concise format is superb. This book will be very useful both for those interested in transfusion medicine and those interested in hemostasis."

-- Ellis Neufeld, MD, PhD, Associate Chief, Division of Hematology/Oncology , Children's Hospital Boston, Associate Professor, Department of Pediatrics, Harvard Medical School, Boston, MA, USA

"This is an outstanding addition to transfusion medicine textbooks. For years we have needed the optimal text for training residents, fellows, and practitioners all in one book. The inclusion of coagulation, laboratory aspects and transfusion medicine was insightful and reflects the multi-disciplinary and clinical identity of Transfusion Medicine."

--Leslie Silberstein, MD, Director, Joint Program in Transfusion Medicine at Children's Hospital Boston, Dana-Farber Cancer Institute, and Brigham and Women's Hospital, Professor of Pathology, Harvard Medical School, Boston, MA, USA

"The book edited by Dr. Christopher Hillyer, Beth Shaz, James Zimring and Thomas Abshire entitled Transfusion Medicine and Hemostasis: Clinical and Laboratory Aspects provides wonderful bite-size comments and clear concise recommendations. This makes for a very practical textbook that should be useful to a wide body of healthcare workers who deal with the use of blood products or patients with bleeding or thrombosis. The coverage of topics in transfusion medicine and coagulation is broad. This is a major advantage of the textbook that makes it particularly useful. The connection between the underlying pathophysiology and the clinical disorders and the treatment recommendations is at the level of just what you want to know. This book is a winner, and I strongly endorse its use by anyone requiring information in this field."

--Michael Laposata, MD, PhD, Pathologist in Chief, Vanderbilt University Hospital, Professor of Pathology and Medicine, Vanderbilt University, Nashville, TN, USA
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Review quote

"Given the cross disciplinary nature of transfusion medicine and the intensive focus on transfusion medicine and hemostasis as evidenced by the Transfusion Medicine, Hemostasis Clinical Trials Network sponsored by NHLBI, this textbook is both timely and needed by practitioners in both clinical and laboratory disciplines. The book is written exclusively by faculty of one of the leading programs in transfusion medicine, hemostasis, and hematology and covers important adult and pediatric concepts in these two fields. I know that hematologists, pathologists, and clinicians who depend upon transfusion and hemostatic support will find this novel text interesting and valuable in their practice and teaching efforts."

--Paul M. Ness, MD, Director, Transfusion Medicine, Johns Hopkins Medical Institutions, Professor of Pathology and Medicine & Oncology, Johns Hopkins University, Baltimore, MD, USA

"Few transfusion medicine texts have given such weight and focus to hemostasis. The combination of clinical and laboratory aspects in a concise format is superb. This book will be very useful both for those interested in transfusion medicine and those interested in hemostasis."

-- Ellis Neufeld, MD, PhD, Associate Chief, Division of Hematology/Oncology , Children's Hospital Boston, Associate Professor, Department of Pediatrics, Harvard Medical School, Boston, MA, USA

"This is an outstanding addition to transfusion medicine textbooks. For years we have needed the optimal text for training residents, fellows, and practitioners all in one book. The inclusion of coagulation, laboratory aspects and transfusion medicine was insightful and reflects the multi-disciplinary and clinical identity of Transfusion Medicine."

--Leslie Silberstein, MD, Director, Joint Program in Transfusion Medicine at Children's Hospital Boston, Dana-Farber Cancer Institute, and Brigham and Women's Hospital, Professor of Pathology, Harvard Medical School, Boston, MA, USA

"The book edited by Dr. Christopher Hillyer, Beth Shaz, James Zimring and Thomas Abshire entitled Transfusion Medicine and Hemostasis: Clinical and Laboratory Aspects provides wonderful bite-size comments and clear concise recommendations. This makes for a very practical textbook that should be useful to a wide body of healthcare workers who deal with the use of blood products or patients with bleeding or thrombosis. The coverage of topics in transfusion medicine and coagulation is broad. This is a major advantage of the textbook that makes it particularly useful. The connection between the underlying pathophysiology and the clinical disorders and the treatment recommendations is at the level of just what you want to know. This book is a winner, and I strongly endorse its use by anyone requiring information in this field."

--Michael Laposata, MD, PhD, Pathologist in Chief, Vanderbilt University Hospital, Professor of Pathology and Medicine, Vanderbilt University, Nashville, TN, USA
show more

About Christopher D. Hillyer

Christopher D. Hillyer, MD, is President and CEO of New York Blood Center and Professor, Department of Medicine, Weill Cornell Medical College, New York, NY. Previously, he was the tenured, endowed Distinguished Service Professor, Department of Pathology and Laboratory Medicine, Emory University School of Medicine and served as director of the Emory Center for Transfusion and Cellular Therapies with responsibility for all aspects of clinical and academic transfusion medicine at Emory's seven principle hospitals. Dr. Hillyer is an editor of twelve textbooks in transfusion medicine, author of over 160 articles pertaining to transfusion, human immunodeficiency virus, and herpes viruses, most notably cytomegalovirus. Nationally recognized as an expert in hematology and blood transfusion, Dr. Hillyer is also a past-president, board of directors of AABB and a former trustee of the National Blood Foundation. Dr. Hillyer has been awarded many million dollars in research funding from the National Institutes of Health, the Centers for Disease Control and Prevention and other agencies. He was an associate editor of Transfusion and serves on several other editorial boards. Dr. Hillyer was formally recognized for his work in Africa as part of the AABB/Emory cooperative agreement from the President's Emergency Plan For AIDS Relief (PEPFAR), and is a recipient of two Tiffany Awards from the American Red Cross where he also served as a medical director and a member of their national Medical Advisory Board. He also received the 2014 Emily Cooley Award from AABB for his "significant commitment and contributions to the field of transfusion medicine through extensive teaching, mentoring and professional leadership, and the countless clinical, scientific and innovative resource materials he has created to educate others". He is a co-founder of Transfusion & Transplantation Technologies, Inc (3Ti) and holds over 20 patents or patents pending. Dr. Hillyer is board certified in transfusion medicine, hematology, medical oncology and internal medicine. He received his BS from Trinity College, and his MD from the University of Rochester School of Medicine, with postgraduate training and fellowships in hematology-oncology, transfusion medicine and bone marrow transplantation at Tufts-New England Medical Center. Beth H. Shaz, MD, is Chief Medical and Scientific Officer, Executive Vice President at New York Blood Center, and Adjunct Assistant Professor, Department of Pathology and Cell Biology, Vagelos College of Physicians and Surgeons, Columbia University. Beth is responsible for all medical and scientific activities throughout the NYBC network, which includes Rhode Island Blood Center, Innovative Blood Resources (Memorial Blood Center and Nebraska Blood Center), Community Blood Center of Greater Kansas City, and Blood Bank of Delmarva. Medical activities comprise of hemophilia services, clinical apheresis services, perioperative autologous transfusion services, cellular therapy, medical education, medical consultation, transfusion services, bone marrow donor recruitment, and donor management. Scientific activities include basic science at the Lindsey F. Kimball Research Institute and Comprehensive Cell Solutions (CCS), which contains translational and clinical research. NYBC's scientific and medical activities focus on transfusion medicine, cell therapy, regenerative medicine, infectious disease, hematology, and personalized medicine. Beth is an editor of ten books in transfusion medicine, author of over 130 articles pertaining to transfusion medicine. She is an associate editor of TRANSFUSION and on the editorial board of BLOOD. Previously, she was an Associate Professor at Emory University School of Medicine and director of the transfusion service at Grady Memorial Hospital. Also, she was an instructor at Harvard Medical School and associate director of the transfusion service at Beth Israel Deaconess Medical Center in Boston. Beth received her MD with research distinction from the University of Michigan and BS in chemical engineering with distinction from Cornell University. She completed a general surgery internship at Georgetown University, an anatomic & clinical pathology residency at Beth Israel Deaconess Medical Center, and a transfusion medicine fellowship at Harvard Medical School.
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