Transactions of the Association of American Physicians Volume 31

Transactions of the Association of American Physicians Volume 31

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This historic book may have numerous typos and missing text. Purchasers can usually download a free scanned copy of the original book (without typos) from the publisher. Not indexed. Not illustrated. 1916 edition. Excerpt: ... chemical alteration in the proteids or lipoids of the plasma. Furthermore, we are impressed with the fact that a large amount of bile pigment and also bile salts may be in the plasma and entirely disappear from the plasma without either salts or pigment ever making their appearance in the urine. A priori, we would say, in view of all these facts, that the plasma has the first call on the biliary elements and holds them with considerable tenacity away from the renal filter and in some instances away from the tissues also. This adsorption of bile pigment by the plasma readily accounts for the disparity generally seen between the concentration of bilirubin in the serum of ascitic fluid and pleural fluid and the subarachnoid fluid, on the one hand, and the concentration of bile pigment in the blood plasma in cases of jaundice, and it also accounts for the fact that large amounts of bilirubin may be found in the serum of fluid contained in the pleural cavity in cases of hemothorax without bilirubin ever appearing in the plasma of the circulatory blood. In other words, whether the bilirubin is adsorbed primarily to plasma within or without the bloodvessels, the plasma does not yield the bilirubin to the vessel wall any more readily than it is yielded to the renal filter or to the collodion sack. However, if we have a normal plasma and a normal liver, the bile pigment and bile salts are readily yielded to the liver, as is clearly shown by animal experiment. The Gmelin test for bilirubin in plasma is not sufficiently delicate to give the blue-green zone in the coagulum when bile is added to the plasma in sufficient amounts to give a visible yellow stain to the plasma. So the best method is to compare the plasma of an animal (before the injection...show more

Product details

  • Paperback
  • 189 x 246 x 9mm | 304g
  • Rarebooksclub.com
  • United States
  • English
  • black & white illustrations
  • 1236878167
  • 9781236878168