A Text-Book of Pathological Anatomy and Pathogenesis Volume 1

A Text-Book of Pathological Anatomy and Pathogenesis Volume 1

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This historic book may have numerous typos and missing text. Purchasers can usually download a free scanned copy of the original book (without typos) from the publisher. Not indexed. Not illustrated. 1883 edition. Excerpt: ...The nodules always contain the characteristic bacilli. In guinea-pigs the first appearance of disease is manifested ten days after inoculation. It may therefore be accepted as an established fact that tuberculosis is an infective disease, induced by the presence of a specific bacillus. In the light of this knowledge, the various theories which have been advanced with regard to the causation of tuberculosis become in some respects irrelevant. It will be matter for further experimental investigation to determine the vital properties of the tubercle-bacillus. Among other points, it will have to be settled whether the bacillus can develope only within the bodies of men and other mammals, or whether it may not pass through some stage of its existence outside the body: in other words, whether the disease is strictly contagious, i.e. transmissible directly from one subject to another; or whether it is due to something of the nature of a miasma--a poison which may develope outside the body. According to Koch, the bacillus can only be bred between the temperatures of 30C and 41C (86F--1058F). If this be so, it is hard to see how it can multiply outside the body. With regard to the transmission of tuberculosis from animals to man, it is to be noted that Koch has found the specific bacillus in the nodular growths which occur in the 'pearly disease' of cattle (Perlsucht or bovine tuberculosis). Clinical experience would seem to indicate that the tuberclebacillus is no ordinary bacterium, such as may enter and affect any organism without distinction. It would seem rather as if infection occurred only where a definite predisposition exists, or where a considerable quantity of the virus is introduced. This predisposition may be local as well as general....
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Product details

  • Paperback | 144 pages
  • 189 x 246 x 8mm | 268g
  • United States
  • English
  • black & white illustrations
  • 1236985559
  • 9781236985552