Telomeres in Health and Disease: Volume 125

Telomeres in Health and Disease: Volume 125

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Description

This special volume of Progress in Molecular Biology and Translational Science focuses on telomeres in health and disease. This volume covers a variety of topics with reviews written by experts in the field.
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Product details

  • Hardback | 202 pages
  • 157.48 x 231.14 x 17.78mm | 453.59g
  • Academic Press Inc
  • San Diego, United States
  • English
  • 012397898X
  • 9780123978981

Table of contents

Telomere and Telomerase Biology
Miriam Aparecida Giardini, Marcela Segatto, Marcelo Santos da Silva, Vinicius Santana Nunes and Maria Isabel Nogueira Cano
Human Telomeres and Telomere Biology Disorders
Sharon A. Savage
Telomere Biology in Stem Cells and Reprogramming
Luis F. Z. Batista
Telomere Dynamics and Aging
Geraldine Aubert
Telomeres in Molecular Epidemiology Studies
Clara Bodelon, Sharon A. Savage and Shahinaz M. Gadalla
Telomere dysfunction and hematologic disorders
Raquel M. A. Paiva and Rodrigo T. Calado
The Role of Telomeres in Liver Disease
Yoshiaki Sunami, Guido von Figura, Alexander Kleger, Pavel Strnad, Norbert Huser and Daniel Hartmann
Telomeres in lung diseases
Rodrigo T. Calado
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Review quote

Praise for the series: "Full of interest not only for the molecular biologist-for whom the numerous references will be invaluable-but will also appeal to a much wider circle of biologists, and in fact to all those who are concerned with the living cell." --British Medical Journal
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About Rodrigo Calado

Rodrigo Calado received his MD in 1997 and PhD in 2003 both from the University of Sao Paulo, Brazil. He was trained in hematology and did his postdoctoral fellowship at the U. S. National Institutes of Health in Bethesda, Maryland with Dr. Neal S. Young, where he also worked as a Staff Scientist between 2007 and 2011. He is currently Associate Professor of Medicine at the University of Sao Paulo in Ribeirao Preto, Brazil. Dr. Calado was the first to report on telomerase enzyme mutations in humans causing disease (aplastic anemia) and found that telomerase complex mutations also predisposed to leukemia and liver cirrhosis. He also demonstrated that short telomeres increase chromosome instability in humans and that sex hormones up-regulate telomerase function in hematopoietic cells.
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