The Surgical Clinics of Chicago Volume 2, No. 6

The Surgical Clinics of Chicago Volume 2, No. 6

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This historic book may have numerous typos and missing text. Purchasers can download a free scanned copy of the original book (without typos) from the publisher. Not indexed. Not illustrated. 1918 edition. Excerpt: ...in almost all purpuras there is hepatic glycosuria. Degeneration of the liver is the cause of the purpura appearing in old tubercular patients. It is known that patients with cirrhosis have a tendency to hemorrhage, and that phosphorus and arsenic intoxication, which affect the liver cells, produce hemorrhagic symptoms. Purpura has been produced in animals by bringing about changes in the liver and nervous system. Lippmann thinks that purpura is bacterial in origin, though this has never been demonstrated. He thinks it is caused by some specific micro-organisms not yet isolated, and that the virus circulating in the blood produces small emboli and hemorrhages, which explains similar findings in typhus, colisepsis, and endocarditis maligna. Burt says that the proximate cause of purpura hemorrhagica is believed to be a hyaline and amyloid degeneration of the walls, both intima and adventitia, of the blood-vessels, with ultimate hemorrhage, and by rupture of the vessels rather than by diapedesis. It seems probable that any unusual pressure of the circulation against the vessels previously weakened by degenerative changes would be sufficient to precipitate the extravasation. Cannata thinks the purpura is due to some organ having a mechanical influence on the circulation; that is, the suprarenal capsule. It is known that the suprarenal capsule produces a substance which has a stimulating action on the musculature of the heart and blood-vessels, and maintains the necessary tone of these organs. This substance--adrenalin--also has a neutralizing action on toxins circulating in the blood. Any disturbance in the normal secretion of these capsules brings about disequilibrium in the circulation and aggravates any toxic infectious process. He concludes that...show more

Product details

  • Paperback | 66 pages
  • 189 x 246 x 4mm | 136g
  • Rarebooksclub.com
  • Miami Fl, United States
  • English
  • black & white illustrations
  • 1236588541
  • 9781236588548