Studies; Reprints Volume 25

Studies; Reprints Volume 25

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This historic book may have numerous typos and missing text. Purchasers can usually download a free scanned copy of the original book (without typos) from the publisher. Not indexed. Not illustrated. 1916 edition. Excerpt: ...that the blood sugar content would be about 7.7 to 7.9 per cent if all the sugar Was in the circulating blood. As a matter of fact the highest blood sugar values in all these experiments ranged from 1.35 to 2.41 per cent, 0! an average of only 1.93 per cent. It is thus evident that the grea- 61' part of the injected sugar left the blood rapidly, in fact before the end of the injection. This disappearance of dextrose from the blood stream went on, then, entirely independently of the abdominal viSC6IflHence neither the glycogenic activity of the liver nor an excessive consumption of sugar by or in any abdominal organ can account for the greater part of the dextrose which so rapidly leaves the blood after intravenous infusion. _ Analysis of Muscle for Carbohydrates.--In a few of these expel'!ments we analyzed skeletal muscles to determine whether sugar had been stored in them. Higher carbohydrates, as well as dextrose were estimated. A few preliminary studies convinced us that the carbohydrate content of normal muscle is not constant. Therefore it was necessary to determine in each experiment the amount f dextrose and higher carbohydrate present in the muscles before and after the injection. In Experiments 55, 56, and 57 the procedure was as follows: One fore-leg was amputated before the injection of dextrose and immediately placed in the refrigerator. At the end of the experiment the animal was killed, the other foreleg removed and also placed in the refrigerator. The muscles were dissected ofl, put through the grinder twice, and extracted with water in the presence of toluene for about 18 hours in the refrigerator. The fluids were then pressed out and the residue again extracted with water for about 2 hours. All more

Product details

  • Paperback | 182 pages
  • 189 x 246 x 10mm | 336g
  • United States
  • English
  • black & white illustrations
  • 1236877993
  • 9781236877994