Special Pathology and Therapeutics of the Diseases of Domestic Animals Volume N . 2
This historic book may have numerous typos and missing text. Purchasers can download a free scanned copy of the original book (without typos) from the publisher. Not indexed. Not illustrated. 1922 edition. Excerpt: ...of bilirubin-calcium, together with the calcium of the epithelia which are desquamating freely, and this process is stimulated by the admixture of inflammatory protein and by the altered chemical composition and consistency of the bile. Under the same conditions carbonates and phosphates of lime are precipitated. On the other hand, the stasis of bile by itself, probably is not of importance in domestic animals, because only cholesterin is precipitated in sterile accumulated bile, and in domestic animals pure cholesterin calculi hardly ever occur; indeed their gallstones are in general poor in cholesterin. Flocculent, granular masses, like sediment or sand, form in the manner just described; if these are not washed away constantly, on account of the existing stasis, the true gallstones form by the constant deposition of layers of bilirubin-calcium and of other crystalline precipitates. In other cases the crystalline precipitates are deposited around animal parasites or their eggs (liver-flukes) or around bits of food which have found their way into the bile passages by accident. Anatomical Changes. The granular precipitates mentioned above are found very often on the mucosa of the bile ducts and in the bile, in the course of liver-fluke disease in ruminants, occasionally upon other foundations in horses. In old eases these masses form rigid, hollow cylinders attached to the walls of the. bile ducts. In horses, cattle and hogs the bile ducts sometimes contain hard cones or cylinders which may be as thick as a finger. In the fresh state they are light or dark brownish-yellow in color and smooth, and when dried, rough and laminated (Kitt). In other cases they are white and composed of chalklike masses containing minute particles of food. Gurlt found...
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