Ribonucleases : Structures and Functions

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This volume provides an overview and analysis of specific members of the ribonuclease superfamily of related proteins with functions ranging from tumor growth and tumor inhibition to self-recognition and neurotoxicity. It highlights the functional diversity of ribonucleases and reveals the emerging research opportunities provided by these enzymes.
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Product details

  • Hardback | 704 pages
  • 157 x 234 x 35mm | 1,144g
  • Academic Press Inc
  • San Diego, United States
  • English
  • colour illustrations
  • 0125889453
  • 9780125889452

Table of contents

"Escherichia coli" ribonucleases - paradigms for understanding cellular RNA metabolism and regulation, A.W. Nicholson; barstar and barnase, R.W. Hartley; RNase T1/RNase T2 family RNases, M. Irie; structures and mechanism of action of cytotoxic ribonuclease 1-sarcin, I.G. Wool; plant ribonucleases, P.A. Bariola and P.J. Green; S-RNases and other plant extracellular ribonucleases, S.K. Parry et al; evolutionary reconstructions in the ribonuclease family, S.A. Benner et al; evolution of vertebrate ribonucleases, J.J. Beintema et al; crystallographic studies of ribonuclease complexes, G.L. Gilliland; NMR solution structures of ribonuclease A and its complexes with mono- and dinucleotides, C. Gonzales et al; seminal ribonuclease - the importance of diversity, G. D'Alessio et al; eosinophil-associated ribonucleases, M.R. Snyder and G.J. Gleich; structure and function of angiogenin, J.F. Riordan; antitumor RNases, R.J. Youle and G. D'Alessio; 2-5A-dependent RNase L:A regulated endoribonuclease in the interferon system, R.H. Silverman; RNA processing RNases in mammalian cells, J. Ross; messenger RNA ribonucleases and mRNA turnover in "Saccharomyces cerevisae", C.E. Browne and A.B. Sachs; ribonuclease inhibitor, J. Hofsteenge.
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