Dedication; List of contributors; Foreword Jan Olav Johannessen; Acknowledgements; Part I. Introduction: 1. Rationale for and overview of the 2nd edition of The Recognition and Management of Early Psychosis Henry J. Jackson, Patrick D. McGorry and Kelly Allott; 2. Diagnosis and the staging model of psychosis Patrick D. McGorry, Kelly Allott and Henry J. Jackson; Part II. Risk and Vulnerability: 3. Genetic vulnerability Daniel Weinberger and Gregor Berger; 4. Environmental vulnerability and genetic-environmental interactions Jim van Os and Richie Poulton; 5. Neurobiological endophenotypes of psychosis and schizophrenia: are there biological markers of illness onset? Christos Pantelis, Murat Yucel, Stephen J. Wood, Warrick J. Brewer, Alex Fornito, Gregor Berger, Tyrone Cannon and Dennis Velakoulis; Part III. At Risk Mental State: 6. At risk mental state and prediction Alison R. Yung, Joachim Klosterkoetter, Barbara Cornblatt and Frauke Schultze-Lutter; 7. At risk mental state: management Lisa J. Phillips, Jean Addington and Anthony P. Morrison; Part IV. Access and Reducing Delay to Treatment: Reducing DUP: 8. Duration of untreated psychosis: definition, measurement and association with outcome Max Marshall, Susy Harrigan and Shon Lewis; 9. Improving the community's mental health literacy as a means of facilitating early intervention Anthony F. Jorm and Annemarie Wright; 10. Pathways to care and reducing treatment delay in early psychosis Ross M. G. Norman and Ashok K. Malla; Part V. The First Episode: 11. Initial assessment and initial pharmacological treatment in the acute phase Martin Lambert; 12. Complete and incomplete recovery from first-episode psychosis Jean Addington, Tim Lambert and Peter Burnett; 13. Preventive strategies in bipolar disorders: identifying targets for early intervention Philippe Conus, Michael Berk, Nellie Lucas, Jose Luis Vazquez-Barquero and Craig Macneil; Part VI. The Critical Period: Other Psychopathology and Comorbidity: 14. Substance misuse in first-episode psychosis Darryl Wade, Leanne Hides, Amanda Baker and Dan Lubman; 15. Suicide prevention in first-episode psychosis Paddy Power and Jo Robinson; 16. Emotional and personality dysfunctions in early psychosis Max Birchwood, John Gleeson, Andrew Chanen, Louise K. McCutcheon, Shona M. Francey and Maria Michail; Part VII. The Critical Period: Specific Interventions: 17. Family intervention in early psychosis Catharine McNab and Don Linszen; 18. Enhancing work functioning in early psychosis Eoin Killackey, Henry J. Jackson, David Fowler and Keith H. Nuechterlein; 19. Relapse prevention in early psychosis John Gleeson, Don Linszen and Durk Wiersma; 20. Treatment resistance in first-episode psychosis Christian G. Huber and Martin Lambert; Part VIII. Service Models: 21. Using research and evaluation to inform the development of early psychosis service models: international examples Meredith Harris, Thomas Craig, Robert B. Zipursky, Donald Addington, Merete Nordentoft and Paddy Power.