Psychoneuroimmunology : Methods and Protocols

Psychoneuroimmunology (PNI) has developed rapidly in the last four decades. As a multidisciplinary area, PNI may provide a scientific basis for mind-body relationships toward the development of personalized and systems medicine. In Psychoneuroimmunology: Methods and Protocols, expert researchers in the field detail methods and protocols geared toward the development of integrative and individualized therapeutics in multiple dimensions from drugs to behaviors. Written in the highly successful Methods in Molecular Biology(TM) series format, the chapters include the kind of detailed description and implementation advice that is crucial for getting optimal results in the laboratory.



Thorough and intuitive, Psychoneuroimmunology: Methods and Protocols aids scientists in continuing to study holistic views for the translation of psychoneuroimmunology into better preventive and personalized medical practice.
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Part I: Stress and Immunity: Biopsychosocial Models





1. The Role of Psychoneuroimmunology in Personalized and Systems Medicine

Qing Yan

2. Psychoneuroimmunology-The Experiential Dimension

Elling Ulvestad

3. Psychosocial Job Stress and Immunity -- A Systematic Review

Akinori Nakata

4. Immune Cells Listen To What Stress is Saying: Neuroendocrine Receptors Orchestrate Immune Function

Harlan P. Jones

5. Physical Activity, Stress Reduction and Mood: Insight into Immunological Mechanisms

Mark Hamer, Romano Endrighi, and Lydia Poole











Part II: Translation of Psychoneuroimmunology into Personalized Medicine: Potential Biomarkers and Clinical Implications











































6. Translational Implications of Inflammatory Biomarkers and Cytokine Networks in Psychoneuroimmunology

Qing Yan



7. Cytokines as Potential Biomarkers for Parkinson's Disease: A Multiplex Approach

Darcy Litteljohn and Shawn Hayley































8. Exploring the Diagnostic Potential of Immune Biomarker Co-expression in Gulf War Illness

Gordon Broderick, Mary Ann Fletcher, Michael Gallagher, Zachary Barnes, Suzanne D Vernon, Nacy Klimas



9. Neuroimmune Mechanisms of Depression in Heart Failure

Jessica A. Jimenez and Paul J. Mills

















10. A Reinterpretation of the Pathogenesis and Cure of Cancer According to the Psychoneuroimmunological Discoveries

Paolo Lissoni



11. Aging Microglia: Relevance to Cognition and Neural Plasticity

Rachel A. Kohman

12. Autism Spectrum Disorders: From Immunity to Behavior

Milo Careaga and Paul Ashwood



Part III. Technologies and Models in Psychoneuroimmunology Studies











13. Mouse Testing Methods in Psychoneuroimmunology: An Overview of How to Measure Sickness, Depressive/anxietal, Cognitive and Physical Activity Behaviors

Jason M. York, Neil A. Blevins, Tracy Baynard, Gregory G. Freund



14. The MRL Model: an Invaluable Tool in Studies of Autoimmunity - Brain Interactions

Boris Sakic



15. Interleukin-2 and the Brain: Dissecting central versus peripheral contributions using unique mouse models

John M. Petitto, Danielle Meola, Zhi Huang

16. Psychoneuroimmunology and Natural Killer Cells: The Chromium Release Whole Body Assay

Mary Ann Fletcher, Zachary Barnes, Gordon Broderick and Nancy G. Klimas



17. The Application of PET Imaging in Psychoneuroimmunology Research

Jonas Hannestad



18. The Vaccination Model in Psychoneuroimmunology Research: A Review

Anna C. Phillips

19. Using Vaccinations to Assess in vivo Immune Function in PsychoneuroimmunologyVictoria E Burns



20. Translational Bioinformatics in Psychoneuroimmunology: Methods and Applications

Qing Yan





17. The Application of PET Imaging in Psychoneuroimmunology Research

Jonas Hannestad



18. The Vaccination Model in Psychoneuroimmunology Research: A Review

Anna C. Phillips

19. Using Vaccinations to Assess in vivo Immune Function in PsychoneuroimmunologyVictoria E Burns



20. Translational Bioinformatics in Psychoneuroimmunology: Methods and Applications

Qing Yan





17. The Application of PET Imaging in Psychoneuroimmunology Research

Jonas Hannestad



18. The Vaccination Model in Psychoneuroimmunology Research: A Review

Anna C. Phillips

19. Using Vaccinations to Assess in vivo Immune Function in PsychoneuroimmunologyVictoria E Burns



20. Translational Bioinformatics in Psychoneuroimmunology: Methods and Applications

Qing Yan





17. The Application of PET Imaging in Psychoneuroimmunology Research

Jonas Hannestad



18. The Vaccination Model in Psychoneuroimmunology Research: A Review

Anna C. Phillips

19. Using Vaccinations to Assess in vivo Immune Function in PsychoneuroimmunologyVictoria E Burns



20. Translational Bioinformatics in Psychoneuroimmunology: Methods and Applications

Qing Yan



18. The Vaccination Model in Psychoneuroimmunology Research: A Review

Anna C. Phillips

19. Using Vaccinations to Assess in vivo Immune Function in PsychoneuroimmunologyVictoria E Burns



20. Translational Bioinformatics in Psychoneuroimmunology: Methods and Applications

Qing Yan
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From the book reviews:
"This is a strategically developed and organized book that compiles the numerous divisions of psychoneuroimmunology (PNI) and aims to relate them to clinical application. ... This book may serve as an attractive authority for those who are dedicated to learning about the integration of body-mind relationships in the realm of medicine. ... It is a valuable tool for students, scientists, physicians, and all those who are on the forefront of medicine." (Sheila Lahijani, Doody's Book Reviews, March, 2013)
show more

From the book reviews:

"This is a strategically developed and organized book that compiles the numerous divisions of psychoneuroimmunology (PNI) and aims to relate them to clinical application. ... This book may serve as an attractive authority for those who are dedicated to learning about the integration of body-mind relationships in the realm of medicine. ... It is a valuable tool for students, scientists, physicians, and all those who are on the forefront of medicine." (Sheila Lahijani, Doody's Book Reviews, March, 2013)
show more