Protein Prenylation, Part A: Volume 29

Protein Prenylation, Part A: Volume 29 : Part A

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This volume of The Enzymes features high-caliber thematic articles on the topic of glycosylphosphatidylinositol (GPI) anchoring of proteins.
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Product details

  • Hardback | 356 pages
  • 152.4 x 231.14 x 25.4mm | 635.03g
  • Academic Press Inc
  • San Diego, United States
  • English
  • New
  • 0123813395
  • 9780123813398

Table of contents

Chapter 1: Protein prenylation: A perspective on initial discoveries

John Glomset

Chapter 2: Insights into the function of prenylation from nuclear lamin farnesylation

Michael Sinensky

Chapter 3: Posttranslational Processing of Nuclear Lamins

Brandon S. J. Davies, Catherine Coffinier, Shao H. Yang, Hea-Jin Jung, Loren G. Fong, and Stephen G. Young

Chapter 4: Prenylated Proteins in Peroxisome Biogenesis

Robert Rucktaschel, Rezeda Mirgalieva, Ralf Erdmann

Chapter 5: Lipid Modification of Ras Superfamily GTPases: Not Just Membrane Glue

Emily J. Chenette,, Channing J. Der

Chapter 6: Heterogeneous Prenyl Processing of the Heterotrimeric G protein Gamma Subunits

John Hildebrandt

Chapter 7: Farnesylation versus geranylgeranylation in G-protein-mediated light signaling

Masahiro Okada , Hidetoshi Kassai, Yoshitaka Fukada

Chapter 8: Organization and function of the Rab prenylation and recycling machinery

Kirill Alexandrov, Yaowen Wu, Wulf Blankenfeldt, Herbert Waldmann, Roger S. Goody

Chapter 9: Protein prenylation and CaaX processing in plants

Shaul Yalovsky

Chapter 10: Posttranslational isoprenylation on tryptophan residue in Bacillus subtilis

Masahiro Okada, Fumitada Tsuji, Youji Sakagami

Chapter 11: Global analysis of prenylated proteins by the use of a tagging via substrate approach

Lai N. Chan, Fuyuhiko Tamanoi

Chapter 12: Global Identification of Protein Prenyltransferase Substrates: Defining the Prenylated Proteome

Corissa L. Lamphear, Elaina A. Zverina, James L. Hougland, Carol A. Fierke

Chapter 13: Structural biochemistry of CaaX protein prenyltransferases

Michael A. Hast , Lorena S. Beese

Chapter 14: Genetic Analyses of the CAAX Protein Prenyltransferases in Mice


Chapter 15: Farnesyl Transferase Inhibitors: From Targeted Cancer Therapeutic to a Potential Treatment for Progeria

W. Robert Bishop, Ronald Doll, Paul Kirschmeier
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About Fuyuhiko Tamanoi

Fuyu Tamanoi is a biochemist who has served on the UCLA School of Medicine and UCLA College faculty since he joined the Department of Microbiology, Immunology & Molecular Genetics in 1993. He became a full professor in 1997. Since 1996, he has been a Director of Signal Transduction Program Area at Jonsson Comprehensive Cancer Center. Dr. Tamanoi earned his B.S. and M.S. in Biochemistry at the University of Tokyo. He received PhD in Molecular Biology at Nagoya University in 1977. He was a postdoctoral fellow at Harvard Medical School, where he worked on bacteriophage DNA replication. From 1980 to 1985, he was a senior staff investigator at Cold Spring Harbor Laboratory, where he worked on adenovirus DNA replication. From 1985 to 1993, he was an Assistant Professor and then Associate Professor at the University of Chicago, where he initiated studies on lipid modification of the Ras family proteins. His laboratory research centers on signal transduction and signal transduction inhibitors. He is currently exploring ways to deliver signal transduction inhibitors using nanoparticles.
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