Progress in Drug Metabolism: v.13

Progress in Drug Metabolism: v.13

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Description

This volume on drug metabolism covers the contribution that transgenic animal research, UDP-glucuronosyltransferases, CNS penetration advances and anticancer drugs can make to the subject.show more

Product details

  • Hardback | 343 pages
  • 156 x 234mm | 850g
  • Taylor & Francis Ltd
  • London, United Kingdom
  • English
  • index
  • 0748400125
  • 9780748400126

Table of contents

Potential applications for transgenic animals in drug development, H.D. Liggitt et al; role of molecular biology in the structural and functional characterization of the UDP-glucuronosyltransferases, M.W.H. Coughtrie; molecular analysis of cytochrome P450s in the CYP2 gene family, C.J. Henderson and C.R. Wolf; CNS penetration of drugs - importance of physiochemical properties, S. Jezequel; azoreduction of drugs an other xenobiotics, W.G. Levine; skin as a xenobiotic metabolizing organ, S.A.M. Hotchkiss; the role of the pharmacokinetic and metabolism studies in anticancer drug discovery and development, A. Gescher and D.R. Newell; the in vivo relevance of in vitro genotoxicity assays incorporating enzyme activation systems, R.D. Combes.show more