Probabilistic Methods for Bioinformatics
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Probabilistic Methods for Bioinformatics : with an Introduction to Bayesian Networks

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Description

The Bayesian network is one of the most important architectures for representing and reasoning with multivariate probability distributions. When used in conjunction with specialized informatics, possibilities of real-world applications are achieved. Probabilistic Methods for BioInformatics explains the application of probability and statistics, in particular Bayesian networks, to genetics. This book provides background material on probability, statistics, and genetics, and then moves on to discuss Bayesian networks and applications to bioinformatics.

Rather than getting bogged down in proofs and algorithms, probabilistic methods used for biological information and Bayesian networks are explained in an accessible way using applications and case studies. The many useful applications of Bayesian networks that have been developed in the past 10 years are discussed. Forming a review of all the significant work in the field that will arguably become the most prevalent method in biological data analysis.
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Product details

  • Hardback | 424 pages
  • 190.5 x 236.22 x 27.94mm | 2,313.31g
  • Morgan Kaufmann Publishers In
  • San Francisco, United States
  • English
  • Approx. 150 illustrations
  • 0123704766
  • 9780123704764
  • 1,257,020

Table of contents

I: Background

Chapter 1: Probabilistic Informatics

Chapter 2: Probability Basics

Chapter 3: Statistics Basics

Chapter 4: Genetics Basics

II: Bayesian Networks

Chapter 5: Foundations of Bayesian Networks

Chapter 6: Further Properties of Bayesian Networks

Chapter 7: Learning Bayesian Network Parameters

Chapter 8: Learning Bayesian Network Structure

III: Bioinformatics Applications

Chapter 9: Nonmolecular Evolutionary Genetics

Chapter 10: Molecular Evolutionary Genetics

Chapter 11: Molecular Phylogenetics

Chapter 12: Analyzing Gene Expression Data

Chapter 13: Genetic Linkage Analysis

Bibliography

Index
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Review Text

"This book provides background material on probability, statistics, and genetics, and then moves on to discuss Bayesian networks and applications to bioinformatics.probabilistic methods used for biological information and Bayesian networks are explained in an accessible way using applications and case studies."-- Zentralblatt MATH 1284-1
"This book provides background material on probability, statistics, and genetics, and then moves on to discuss Bayesian networks and applications to bioinformatics.probabilistic methods used for biological information and Bayesian networks are explained in an accessible way using applications and case studies."-- Zentralblatt MATH 1284-1
show more

Review quote

"This book provides background material on probability, statistics, and genetics, and then moves on to discuss Bayesian networks and applications to bioinformatics...probabilistic methods used for biological information and Bayesian networks are explained in an accessible way using applications and case studies."--Zentralblatt MATH 1284-1
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About Richard E. Neapolitan

Richard E. Neapolitan is professor and Chair of Computer Science at Northeastern Illinois University. He has previously written four books including the seminal 1990 Bayesian network text Probabilistic Reasoning in Expert Systems. More recently, he wrote the 2004 text Learning Bayesian Networks, the textbook Foundations of Algorithms, which has been translated to three languages and is one of the most widely-used algorithms texts world-wide, and the 2007 text Probabilistic Methods for Financial and Marketing Informatics (Morgan Kaufmann Publishers).
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