Principles of Regenerative Medicine

Principles of Regenerative Medicine

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Virtually any disease that results from malfunctioning, damaged, or failing tissues may be potentially cured through regenerative medicine therapies, by either regenerating the damaged tissues in vivo, or by growing the tissues and organs in vitro and implanting them into the patient. Principles of Regenerative Medicine discusses the latest advances in technology and medicine for replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure.
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Product details

  • Hardback | 1472 pages
  • 218.44 x 279.4 x 55.88mm | 3,152.45g
  • Academic Press Inc
  • San Diego, United States
  • English
  • Revised
  • 3rd Revised edition
  • 0123694108
  • 9780123694102

Table of contents

Introduction to Regenerative Medicine

1
Current and Future Perspectives of Regenerative Medicine
Anthony Atala
Mark E. Furth

2
Fundamentals of Cell-Based Therapies
Ross Tubo

3
Stem Cell Research in Regenerative Medicine
Robert M. Nerem
AM Doyle
T Ahsan

Biologic and Molecular Basis of Regenerative Medicine

4
Molecular Organization of Cells
Carol A. Erickson
Jon D. Ahlstrom

5
Cell-ECM Interactions in Repair and Regeneration
Manuela Martins-Green
M. Petreaca

6
Developmental Mechanisms of Regeneration and Strategies of Regenerative Medicien
David L. Stocum

7
Molecular Basis of Pluripotency
Ali H. Brivanlou
Ariel J. Levine

8
How Cells Change Their Phenotype
Peter Andrews
Paul J. Gokhale

9
Somatic Cloning and Epigenetic Reprogramming in Mammals
Heiner Niemann
Christine Wrenzycki
Wilfried A. Kues
Andrea Lucas-Hahn
Joseph W. Warnwath

10
Transgenic Cloned Goats and Cows for the Production of Therapeutic Proteins
Harry Meade
William Gavin
LiHow Chen
David L. Melican
Carol A. Ziomek
Yann Echelard

Cells and Tissue Development

11
Genetic Approaches in Human Embryonic Stem Cells and Their Derivatives: Prospect for Regenerative Medicine
Mickie Bhatia
Junfeng Ji
Bonan Zhong

12
Embryonic Stem Cells: Derivation and Properties
James Thomson
Junying Yu

13
Stem Cells Derived from Amniotic Fluid and Placenta
Paolo De Coppi
Georg Van Dyke
M. Minhaj Siddiqui
Anthony Atala

14
Stem Cells Derived from Cord Blood
Julie Allickson

15
Multipotent Adult Progenitor Cells: Isolation and Induction
Catherine Verfaillie

16
Bone Marrow Stem Cells: Properties and Pluripotency
Ren Ke Li
Munira Xaymardan
Massimo Cimini
Richard D. Weisel

17
Hematopoietic Stem Cells: Properties , Markers and Therapeutics
M.A Goodell
S.M. Chambers
K.K. Lin

18
Neural Stem Cells: Multipotency Beyond Self-renewal and Phenotypic Differentiation
Evan Snyder
Yang D. Teng
Peter M. Black
F.N. Santos
Deniz Konya
Kook In Park
Richard L. Sidman

19
Mesenchymal Stem Cells
Daniel Gazit
Zumila Gazit
Hadi Aslan
Yossi Gafni
Nadav Kimelman
Gadi Pelled

20
Stem Cells and Maturational Lineage Biology: Implications for Clinical, Research and Commercial Programs
Lola Reid
Hsin-lei Yao
N. Cheng

21
Skeletal Muscle Stem Cells
Helen Blau
Jason H. Pomerantz

22
Islet Cell Therapy and Pancreatic Stem Cells
Camillo Ricordi
Juan Dominguez-Bendala
Antonello Pileggi

23
Regenerative Medicine for Diseases of the Retina
Thomas A. Reh
Deepak Lamba

24
Peripheral Blood Stem Cells
Shay Soker
Gunter Schuch
J. Koudy Williams

25
Prospects of Somatic cell Nuclear Transfer Derived Embryonic Stem Cells in Regenerative Medicine
Jose Cibelli
Z. Beyhan

26
Somatic Cells: Growth and Expansion Potential of T Lymphocytes
Rita B. Effros

27
Mechanical and Chemical Determinants of Tissue Development
David Kaplan
Jonathan A. Kluge
Gary G. Leisk

28
Morphogenesis, Bone morphogenetic Proteins and Regenerative Medicine
A. Hari Reddi

29
Physical Stress as a Factor in Tissue Growth and Remodeling
Robert Guldberg
Christopher S. Gemmiti
Yash Kolambkar
Blaise Porter

30
Engineering Cellular Microenvironments
Christopher S. Chen
Wendy F. Liu
Elliot E. Hui
Sangeeta N. Bhatia

31
Applications of Nanotechnology for Regenerative Medicine
Ben Harrison

32
Gene Chips in Regenerative Medicine
Jason Hipp
Anthony Atala

Biomaterials for Regenerative Medicine

33
Design Principles in Biomaterials and Scaffolds
Tae Gwan Park
Hyukjin Lee

34
Natural Polymers
Stephen Badylak

35
Synthetic Polymers
A.G. Mikos
M.C. Hacker

36
Hybrid, Composite, and Complex Biomaterials for Scaffolds
Hae Bang Lee
Gilson Khang
Hee Kim
Moon Suk Kim

37
Surface Modification of Biomaterials
Andres Garcia

38
Cell-Substrate Interactions in Regenerative Medicine
Kam W. Leong
Aparna Nori
Evelyn K.F. Yim
Sulin Chen

39
Histogenesis in Three Dimensional Scaffolds
Jennifer West
Nicole M. Bergman

40
Biocompatibility and Bioresponse to Biomaterials
James Anderson

41
Healing
William J. Lindblad

42
Precision Control of Proteins at Interfaces for Tissue Engineering and Regenerative Medicine
Buddy Ratner

Therapeutic Applications: Cell Therapy

43
Biomineralization and Bone Regeneration
Peter X. Ma
Jiang Hu
Xiaohua Liu


44
Blood Substitutes: Reverse Evolution from Oxygen Carrying to Non-Oxygen Carrying Plasma Expanders
Mark Van Dyke
Amy Tsai
Marcos Intaglietta

45
Articular Cartilage
Myron Spector
Francois Ng kee Kwong

46
Implantation of myogenic Cells in Skeletal Muscles
Jacques Tremblay
Daniel Skuk

47
Clinical Islet Transplantation
A.M. James Shapiro
Juliet A. Emamaulle

48
Cell-Based Repair for Regeneration and Neovascularization: What, Why, How and Where are We Going in the Next 5 - 10 Years?
Andrey G. Zenovich

49
Retinal pigment epithelium derived from embryonic stem cells
Irina Klimanskaya

50
Cell Therapies for Bone Regeneration
Scott P. Bruder
Rehan N. Khanzada
Chantal E. Holy
F. Jerry Volenec

51
Cell-Based Therapies for Musculoskeletal Repair
Rocky Tuan
Wan -Ju Li
David P. Patterson
George T.J. Huang
Kiran Gollapudi

52
Hepatocyte Transplantation
Steven C. Strom
Ewa C.S. Ellis

53
Bioartificial Livers
Lola Reid
Randall E. McClelland

54
Neuronal Transplantation for Stroke
Douglas Kondziolka
Lawrence Wechsler

55
Cell-Based Drug Delivery
Grace Lim

Therapeutic Applications: Tissue Therapy

56
Fetal Tissues
Chester Koh
Seyung Chung

57
Engineering of Large Diameter Vessels
George Christ
Saami K. Yazdani

58
Engineering of Small Diameter Vessels
Robert Tranquillo
Chrysanthi Williams

59
Vascular Assembly in Engineered and Natural Tissues
Larry V. McIntire
Eric M Brey

60
Cardiac Tissue
Michael V. Sefton
Milica Radisic

61
Regenerative Medicine in the Cornea
May Griffith
Heather Sheardown

62
Alimentary Tract
Mike Chen

63
Liver Cell-based Therapy in Regnerative Medicine - Bioreactors as Enabling Technology
Jorg Gerlach
Mariah Hout
Keneth Gage
Katrin Zeilinger

64
Kidney-Intracorporeal
James Yoo

65
Kidney
H. David Humes
William H. Fissell

66
Genitourinary System
Anthony Atala

67
Tissue Engineering of the Reproductive System
Roger De Filippo

68
Therapeutic Opportunities for Bone Grafting
Jeffrey O. Hollinger
John P. Schmitz
Thomas A. Einhorn
Gary E. Friedlaender
Chris R. Brown
Scott D. Bowden
Samuel Lynch

69
Cartilage Tissue Engineering
Jennifer Elisseeff
Paulesh Shah
Alexander Hillel
Ronald Silverman

70
Phalanges and Small Joints
Makoto Komura
James Yoo

71
Functional Tissue Engineering of Ligament and Tendon Injuries
Savio L.-Y. Woo
Alejandro J. Almarza

72
Tissue Therapy: Implications of Regenerative Medicine for Skeletal Muscle
Johnny Huard
Shen Wei

73
Central Nervous System
Molly Shoichet
Jordan H. Wosnick
M. Douglas Baumann

74
Peripheral Nerve Regeneration
Ravi Bellamkonda
Mahesh C. Dodla

75
Dental Tissue Engineering
Pamela Yelick
Yan Lin

76
Innovative Regenerative Medicine Approaches to Skin Cell-Based Therapy for Patiens with Burn Injuries
Jorg Gerlach
Steven E. Wolf
Christa Johnen
Bernd Hartman

77
Military Needs and Solutions in Regenerative Medicine
Alan Russell
Sara Wargo

Regulations and Ethics

78
Ethical Considerations
Louis M. Guenin

79
Religious Considerations
Laurie Zoloth

80
U.S. Stem Cell Research Policy: An Introduction
Josephine Johnston

81
Overview of FDA Regulatory Process
Celia Witten
Ashok Batra
Charles N. Durfor
Stephen H. Hilbert
Davis S. Kaplan
Donald Fink
Deborah Vavoie
Ellen Maher
Richard McFarland

82
Current Issues in U.S. Patent Law
Patrea Pabst
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About Robert M. Nerem

Dr. Atala is an associate professor of surgery and the Director of the Laboratory for Tissue Engineering and Cellular Therapeutics at Children's Hospital and Harvard Medical School in Boston. He is a surgeon, researcher, and expert on tissue engineering and stem cell biology. Dr. Atala has received numerous awards and honors, including the U.S. Congress-funded Christopher Columbus Foundation Award, bestowed on a living American who is currently working on a discovery that will significantly affect society. Robert Lanza, M.D. is currently vice president of research & scientific development at Advanced Cell Technology, and Adjunct Professor of Surgical Sciences at Wake Forest University School of Medicine. He has several hundred scientific publications and patents, and 16 books, including Principles of Tissue Engineering (1st and 2nd Editions), Methods of Tissue Engineering, Principles of Cloning, XENO, Yearbook of Cell & Tissue Transplantation, One World: The Health & Survival of the Human Species in the 21st Century (as editor, with forewords by C. Everett Koop and former President Jimmy Carter), and Medical Science & the Advancement of World Health. Dr. Lanza received his B.A. and M.D. degrees from the University of Pennsylvania, where he was both a University Scholar and Benjamin Franklin Scholar. He is a former Fulbright Scholar, and studied as a student in the laboratory of Richard Hynes (MIT), Jonas Salk (The Salk Institute), and Nobel laureates Gerald Edelman (Rockefeller University) and Rodney Porter (Oxford University). He also worked closely (and coauthored a series of papers) with the late Harvard psychologist B.F. Skinner and heart transplant pioneer Christiaan Barnard. Dr. Lanza's current area of research focuses on the use of stem cells in regenerative medicine.
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