Principles and Practice of Bioanalysis

Principles and Practice of Bioanalysis

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Description

Analysis of small molecules in a biomatrix is carried out by a vast range of institutions for a variety of purposes, from pharmaceutical and agrochemical companies to hospital biochemistry labs and university departments, from environmental monitoring to safety and toxicity testing of new drugs. The range of analytes is enormous, including endogenous peptides such as enkephalins and xenobiotics from the pharmaceutical and agrochemical industries. Bioanalytical science is a rapidly growing field that, in the past, has lacked an accessible and integrated approach to the full range of analytical techniques available.This book provides comprehensive information and guidance on the methods and strategies used in developing and running ultra-trace analyses for drugs, metabolites and other substances. The contributors are experienced research scientists.show more

Product details

  • Hardback | 382 pages
  • 178.3 x 251.5 x 28.4mm | 1,084.86g
  • Taylor & Francis Ltd
  • London, United Kingdom
  • English
  • 125 black & white tables
  • 0748408428
  • 9780748408429

Table of contents

Physico-chemical properties of drugs and metabolites and their extraction from biological material. Solid phase extraction. Basic HPLC theory and practice. HPLC optimization. HPLC detectors. Gas chromatography-what it is and how we use it. Thin layer chromatography. Capillary electrophoresis. Immunoassay techniques. Automation of sample preparation. Fundamental aspects of mass spectrometry ...overview terminology... Applications of mass spectrometry: quantitative mass spectrometry.show more

About Richard Venn

Venn; Richard F. Pfizer Central Research, Sandwich, UK,show more