Principles of Molecular Cardiology
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Principles of Molecular Cardiology

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An easy-to-read survey of all the latest developments in molecular cardiologic research and therapy. The authors explain in a readable style the complex process of the heart's development, the molecular basis of cardiovascular diseases, and the translation of these research advances to actual clinical treatments. The expert information provided here serves as an invaluable building block for novel treatments of cardiovascular diseases and includes a comprehensive discussion of cardiac function and dysfunction, coronary artery disease, cardiac arrhythmias, vascular diseases, and risk factors for cardiovascular disease. These state-of-the-art approaches to molecular cardiologic research include critical discussion of such topics as the molecular events that regulate angiogenesis and the potential for angiogenic therapy, emerging therapies for arrhythmias, and a description of the molecular biology of aging and its impact on the cardiovascular system.show more

Product details

  • Hardback | 617 pages
  • 224 x 286 x 34mm | 2,218.09g
  • Humana Press Inc.
  • Totowa, NJ, United States
  • English
  • Illustrated
  • 2005 ed.
  • XIII, 617 p.
  • 1588292010
  • 9781588292018

Review quote

From the Foreword..."I believe that this is an outstanding book. Anyone interested in the development, genetics, and pathologies that affect the cardiovascular system will want to have Principles of Molecular Cardiology available for ready reference." -James T. Willerson, MD From the reviews: "...should be in any pediatric library, not to say cardiac departments." - Pediatric Endocrinology Reviews "This book ... provides a broad and up-to-date treatment of molecular biology of cardiovascular diseases. Certainly this book shows quite thoroughly the direction in which cardiology is moving." (American Journal of Cardiology, December, 2005) "...shows quite thoroughly the direction in which cardiology is moving." -American Journal of Cardiologyshow more

Back cover copy

In recent years our understanding of the genetic links to cardiovascular disease has increased dramatically, helping to redefine the etiology and diagnostic criteria for numerous conditions, and allowing the development of novel, individualized treatments. In Principles of Molecular Cardiology leading specialists explore all the latest developments in molecular cardiologic research and therapy. The authors explain in a concise yet readable style the complex process of the heart's development, the molecular bases of cardiovascular diseases, and the translation of these research advances to actual clinical treatments. The expert information provided here serves as an invaluable building block for novel treatments of cardiovascular diseases, and includes a comprehensive discussion of cardiac function and dysfunction, coronary artery disease, cardiac arrhythmias, vascular diseases, and risk factors for cardiovascular disease. These state-of-the-art approaches to molecular cardiologic research include critical discussion of such topics as the molecular events that regulate angiogenesis and the potential for angiogenic therapy, emerging therapies for arrhythmias, and a description of the molecular biology of aging and its impact on the cardiovascular system. Authoritative and up-to-date, Principles of Molecular Cardiology offers cardiovascular scientists and fellows not only a quick yet insightful tour from bench to bedside of the molecular mechanisms underlying cardiovascular disease, but also an introduction to the just-now emerging therapies based on our enriched understanding of the heart's molecular biology and genetics.show more

Table of contents

Part I. Overview Cardiovascular Genetics Christopher Semsarian and Christine Seidman Molecular Biology Applications in Cardiovascular Medicine Eugene Yang, Scott M. Wasserman, Tatsuro Ishida, Raymond Tabibiazar, and Thomas Quertermous Genomics and Its Application to Cardiovascular Disease Robert Roberts Gene Therapy and Cardiovascular Diseases Yi Chu, Neal L. Weintraub, and Donald D. Heistad Stem Cells and Progenitor Cells in Cardiovascular Disease Jalees Rehman and Keith L. March Part II. Myocardial Disease Development of the Vertebrate Heart Mabelle Ashe and David Bader Inherited Myocardial Diseases Elizabeth M. McNally Receptor-Signaling Pathways in Heart Failure Shayela Suvarna, Liza Barki-Harrington, Miwako Suzuki, Philippe Le Corvoisier, and Howard A. Rockman Recent Insights into the Molecular Pathophysiology of Viral Myocarditis Tony Tran, Roger D. Rossen, and Douglas L. Mann Genetic Underpinnings of Cardiogenesis and Congenital Heart Disease Vidu Garg and Deepak Srivastava Part III. Coronary Artery Disease Coronary Artery Development Mark W. Majesky Atherosclerosis George A. Stouffer Antiplatelet Drugs Karlheinz Peter Myocardial Infarction D. Douglas Miller and Steven C. Herrmann Transplant Arteriopathy: Pathology, Pathogenesis, and Prospects for Treatment Joannis Vamvakopoulos, Einari Aavik, Daniel du Toit, Pekka Hayry, and Minnie Sarwal Thrombolysis: Scientific Basis for Current Therapy Guy L. Reed III Coronary Restenosis Julius Aitsebaomo, Martin Moser, Susan Smyth, and Cam Patterson Part IV. Arrhythmias Induction and Patterning of Purkinje Fiber Network Takashi Mikawa, Robert G. Gourdie, Kimiko Takebayashi-Suzuki, Nobuyuki Kanzawa, DavidJ. Pennisi, Clifton P. Poma, and Maxim Shulimovich Mechanisms of Sudden Cardiac Death Wayne E. Cascio Gene Therapy for Cardiac Arrhythmias J. Kevin Donahue and Eduardo Marban Genetics and Arrhythmias Kui Hong and Ramon Brugada Part V. Vascular Diseases Therapeutic Angiogenesis for Ischemic Vascular Disease Jai Pal Singh and J. Anthony Ware Nitric Oxide in Cardiovascular Biology and Pathophysiology Marshall A. Corson Vasculitis Ronald J. Falk and J. Charles Jennette Primary Pulmonary Hypertension Evangelos D. Michelakis and Stephen L. Archer The Molecular Basis of Cerebrovascular Malformations Douglas A. Marchuk Thrombotic Vascular Disease Stephan Moll and Gilbert C. White II Part VI. Risk Factors Risk Factors Ngoc-Anh Le and W. Virgil Brown Vascular Aging: From Molecular to Clinical Cardiology Samer S. Najjar and Edward G. Lakatta Oxidative Stress Nageswara R. Madamanchi and Marschall S. Runge Diabetes Mellitus: An Important Cardiovascular Risk Factor David R. Clemmons Vascular Inflammation as a Cardiovascular Risk Factor Allan R. Brasier, Adrian Recinos III, and Mohsen S. Eledrisi Indexshow more

Review Text

From the Foreword... "I believe that this is an outstanding book. Anyone interested in the development, genetics, and pathologies that affect the cardiovascular system will want to have Principles of Molecular Cardiology available for ready reference." -James T. Willerson, MD From the reviews: "...should be in any pediatric library, not to say cardiac departments." - Pediatric Endocrinology Reviews "This book ... provides a broad and up-to-date treatment of molecular biology of cardiovascular diseases. Certainly this book shows quite thoroughly the direction in which cardiology is moving." (American Journal of Cardiology, December, 2005) "...shows quite thoroughly the direction in which cardiology is moving." -American Journal of Cardiologyshow more

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