Prevention of Progression in Chronic Liver Disease

Prevention of Progression in Chronic Liver Disease : An Update on SNMC (Stronger Neo-Minophagen C). In honour of Hans Popper's 100th birthday

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In several liver diseases, the underlying cause cannot always be eliminated, i.e. the progression of liver disease cannot be prevented. This is particularly true for non-responders to the treatment of chronic hepatitis C (HCV). It is relevant for more than 40% of patients with HCV genotype 1 and up to 20% of patients with genotype 2 or 3. Several approaches are now underway to prevent or ameliorate mechanisms of disease progression. In Asia, and particularly in Japan, Glycyrrhizine-SNMC has been widely used for this purpose. At present, SNMC is under clinical evaluation in Europe.
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Product details

  • Hardback | 130 pages
  • 155 x 235 x 9.65mm | 830g
  • Dordrecht, Netherlands
  • English
  • 2004 ed.
  • VIII, 130 p.
  • 0792387961
  • 9780792387961

Table of contents

List of Principal Authors. Preface. Introduction; H Suzuki. 1: Mechanisms of fibrogenesis; B Stefanovic, J Lindquist, RA Rippe, B Schnabl, R Schwabe, R Bataller, DA Brenner. 2: Non-invasive markers of liver injury; V Ratziu, T Poynard. 3: Complications of cirrhosis: the relevance of hepatocellular carcinoma; M Colombo, M Iavarone. 4: Controlling necroinflammation of liver with SNMC (Stronger Neo Minophagen C): therapy on interferon non-responders; S Lino. 5: Predictive parameters of non-response to standard hepatitis treatment; H Wedemeyer. 6: Concepts for the treatment of non-responders in hepatitis C; S Zeuzem. 7: Glycyrrhizin: the molecule and present knowledge of action in various liver diseases; K Shiraki, H Sato, M Kurokawa, Y Yoshida. 8: Dendritic cells in immune responses against hepatitis C virus; N Hayashi, T Kanto, T Takehara. 9: SNMC in the prevention of cirrhosis and hepatocellular carcinoma: Japanese experience; K Ikeda. 10: SNMC in interferon non-responders with chronic hepatitis C: European experience in controlled trials; S Schalm, TGF van Rossum, H Orlent, BE Hansen. Index
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