The Practitioner Volume 79

The Practitioner Volume 79

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This historic book may have numerous typos and missing text. Purchasers can usually download a free scanned copy of the original book (without typos) from the publisher. Not indexed. Not illustrated. 1907 edition. Excerpt: ...far more energetic. Hypodermic injection is, in man, the best method of administration.' A sterile injection of 40 c.c. of normal saline, containing dissolved in it 40 c.g. of nucleinate of sodium, made in one or two convenient places, the flanks or the outer surface of the thighs, causes in a few hours some local pain, which can be allayed by the application of opium fomentations. After twenty-four hours, a slight amount of swelling and redness appears, but has disappeared by the following day. Two or three days later, a second injection is given, and a third, _later on, the dose being diminished in each instance. There is, in this way, kept up a hyperleucocytosis favourable to the fight undertaken. Nucleinate of sodium appears to act by a quick and somewhat lasting increase in the function of phagocytosis. Its mode of action is powerful, and must be proportioned to the nature of the case. The increase in the leucocytes is chiefly in the mono-nuclear type, and is found in six to eight hours after injection. It continues to increase for about forty-eight hours, and lasts for four or five days, decreasing slowly. Chantemesse determined the opsonic index to be 1 '60 before, and 2'50, twenty-four hours after the injection of nucleinate of sodium, in the case of a man suflering from perforation. Clinically, the following facts were noted. In typhoid patients, who, after haemorrhage from the bowel, complained of sharp pains in the abdomen, with retraction and rigidity of the abdominal walls, and loss of hepatic dulness, an injection of nucleinate, made as soon aspossible after the first appearance of the pains, brought about, at the end of twenty-four hours, the complete, or almost complete, cessation of the pains. On the next day, more

Product details

  • Paperback | 328 pages
  • 189 x 246 x 18mm | 585g
  • United States
  • English
  • black & white illustrations
  • 1236813944
  • 9781236813947