The Practice of Medicinal Chemistry

The Practice of Medicinal Chemistry

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This book collects in one single volume, the practical aspects of Medicinal Chemistry, seen from a chemical point of view, including the wealth of information which chemists accumulate over a career, but generally is never organized and presented in a coherent form in print. Emphasis is given to how medicinal chemists conduct their search for, and design of, new drug entities. In contrast to other books on the market, it focuses on the chemistry, rather than pharmacological concepts or description of the various therapeutic classes of drugs. It should become a standard reference on the tools available to medicinal chemists when designing new drugs.
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Product details

  • Hardback | 896 pages
  • 167.64 x 246.38 x 53.34mm | 1,973.12g
  • Academic Press Inc
  • San Diego, United States
  • index
  • 0127446400
  • 9780127446400

Table of contents

General aspects of medicinal chemsitry; drug targets and lead compound discovery strategies; primary exploration of structure-activity relationships; substituents and functions - qualitative and quantitative aspects of structure-activity relationships; spatial organization, receptor mapping and molecular modelling; chemical modifications influencing the pharmacokinetic properties; pharmaceutical and chemical formulation problems; development of new drugs - legal and economic aspects.
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Review quote

..".The editor-author and his contributors have succeeded admirably in producing a useful, authoritative discussion of the principles and practice of medicinal chemistry...the volume has a useful index, is well produced, and is very reasonably priced..."--JOURNAL OF MEDICINAL CHEMISTRY
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