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This book was awarded the 2002 Best New Book in Medical Science - Professional/Scholarly Publishing Division of the Association of American. "Publishers Platelets" is a comprehensive new textbook of 61 chapters and 1,100 pages (approx.) written by over 100 world leaders in the field. "Platelets" is a single definitive source of state-of-the-art knowledge about platelets. There has been no textbook that specifically and fully covers the entire field of platelet biology and clinical medicine. "Platelets" now fills this need. "Platelets" encompasses: platelet biology; platelet function testing; the role of platelets in disease; inherited and acquired disorders of platelet number and function; pharmacology of antiplatelet agents; pharmacology of agents to increase platelet numbers and/or function; platelet transfusion medicine; and gene therapy. The intended audience for "Platelets" includes haematologists, cardiologists, stroke physicians, blood bankers, pathologists, and researchers in thrombosis and haemostasis as well as students and fellows in these fields.
This is a single comprehensive source of state-of-the-art knowledge about platelets with over 100 contributing authors from 13 countries. The authors of each chapter are world leaders in their fields. It is the definitive resource with 61 chapters, 1,100 pages (approx.), 12,000 references (approx.), 70 full color figures, 140 black and white figures, and 95 tables.
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Product details

  • Hardback | 704 pages
  • 221.5 x 287 x 50mm | 2,812.31g
  • Academic Press Inc
  • San Diego, United States
  • English
  • Illustrated
  • Illustrated edition
  • Illustrations (some col.)
  • 0124939511
  • 9780124939516

Review quote

"...this book, with its scope and depth, has much to offer clinicians, laboratory hematologists and academic researchers alike who are actively involved with platelets. ...arguably the most complete compendium available on the subject that was once regarded as merely 'blood dust'. The volume will make a valuable addition to hematology, departmental and institutional libraries alike as a definitive reference." -BRITISH JOURNAL OF HAEMATOLOGY (2003) "...a must have for the shelf of physicians and scientists with more than a passing interest in platelet pathophysiology." -LABORATORY HEMATOLOGY (2003) "... most up-to-date comprehensive standard work, which provides a superb reference for everyone interested in platelets." -PATHOPHYSIOLOGY OF HAEMOSTASIS AND THROMBOSIS (November 2003) "If you have no time to waste and want a book that is easy to read, concise, and to the point, then Platelets is the book for you." -ARCH PATHOL LAB MED (November 2003) "This 'tome' will be an excellent source for medical students who wish to specialize in transfusion medicine, as well as for practitioners in the field looking for a single-handed compilation of authoritative material for refreshing their knowledge." -TRANSFUSION (December 2003) " attractive and comprehensive compendium that is one of the first to appear on this important subject in more than a decade...Platelets will be a highly valued contemporary information resource both for scientists and investigators with an interest in one or more aspects of platelets...the book should be a component of medical and scientific libraries, as well as the specialized collections of those with clinical and research interests in platelets." -INTERNATIONAL SOCIETY ON THROMBOSIS AND HAEMOSTASIS (2003) "...stands out as the most comprehensive and up-to-date review of platelets yet published." JOURNAL OF VASCULAR SURGERY "A hefty, comprehensive reference comprising 61 contributed chapters on those small cells with big roles." SCITECH BOOK NEWS (December 2002) "Platelets is an excellent, beautifully organized text. The authors are the best in the world, and their efforts to provide definitive information on a broad range of subjects belnd well. Presentation is excellent. Without a doubt, the text will serve as a definitive resource for years to come." -DEPARTMENT OF LABRATORY MEDICINE AND PATHOLOGY, AND PEDIATRICS (2003) "The book has many strengths...will find a place in many libraries, both general medical and personal collections. The material is of self sufficient quality and scope that many chapters will retain their value for years to come." -SEATTLE VETERANS HOSPITAL (2003)
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About Alan Michelson

Dr. Alan D. Michelson is Director of the Center for Platelet Function Studies, Professor of Pediatrics, Medicine and Pathology, and Vice Chair for Academic Affairs in the Department of Pediatrics at the University of Massachusetts Medical School in Worcester, Massachusetts, U.S.A. He received his medical degree from the University of Adelaide, Australia in 1973. Dr. Michelson continued his medical training on a Fulbright Scholarship at Harvard Medical School, Brigham and Womens Hospital, and Childrens Hospital, all in Boston, Massachusetts. He has published over 300 original research articles, original research abstracts, and invited reviews. He has been the principal investigator on over 70 grants. Dr. Michelson has been an invited speaker at over 100 major medical conferences worldwide. He is Chairman of the Platelet Physiology Scientific Subcommittee of the Scientific and Standardization Committee (SSC), International Society on Thrombosis and Haemostasis (ISTH). Dr. Michelson has been an invited participant at 13 international consensus conferences and workshops, including the Antithrombotic and Thrombolytic Therapy: ACCP Evidence-Based Clinical Practice Guidelines (1995 present). Dr. Michelson is the inventor of 2 U.S. patents.
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Table of contents

Foreword: A Brief and Highly Selective History of Ideas About Platelets in Health and Disease. Barry S. Coller Part One: Biology The Evolution of Mammalian Platelets. Megakaryocyte Development and Platelet Formation. Platelet Structure. Platelet Turnover and Aging. Platelet Receptors. The GPIb-IX-V Complex. Integrin aIIbb3. Thrombin Receptors. P-Selectin/PSGL-1 and Other Interactions Between Platelets, Leukocytes, and Endothelium. Platelet Polymorphisms. Platelet Secretion. Signal Transduction During the Initiation, Extension, and Perpetuation of Platelet Plug Formation. Platelet Thrombus Formation in Flowing Blood. Interactions Between Platelets and the Coagulation System. Platelet-Derived Microparticles. Platelet Function in the Newborn. Part Two: Tests of Platelet Function Platelet Count. The Bleeding Time. Platelet Aggregation. Flow Cytometry. Ultegra Rapid Platelet Function Analyzer. Platelet Function Analyzer (PFA)-100. Cone and Plate(let) Analyzer. Perfusion Chambers. Animal Models. Part Three: The Role of Platelets in Disease Atherosclerosis and Coronary Artery Disease. Ischemic Cerebrovascular Disease. Peripheral Vascular Disease. Diabetes Mellitus. Renal Disease. Inflammation. Antimicrobial Host Defense. Tumor Growth and Metastasis. Alzheimer Disease. Psychiatric Disorders. Part Four: Disorders of Platelet Number and Function The Clinical Approach to Disorders of Platelet Number and Function. Immune Thrombocytopenic Purpura. HIV-1-related Thrombocytopenia. Heparin-induced Thrombocytopenia. Drug-induced Thrombocytopenia. Thrombotic Thrombocytopenic Purpura and Hemolytic-Uremic Syndrome. Thrombocytopenia in Pregnancy. Thrombocytopenia in the Newborn. Pseudothrombocytopenia. Thrombocytosis and Essential Thrombocythemia. Inherited Disorders of Platelet Function. Acquired Disorders of Platelet Function. Cardiopulmonary Bypass. Part Five: Pharmacology: Antiplatelet Therapy Aspirin. GPIIb-IIIa Antagonists. Clopidogrel and Ticlopidine. Dipyridamole. Cilostazol. Part Six: Pharmacology: Therapy to Increase Platelet Numbers and/or Function Thrombopoietin. Interleukin 11. Desmopressin. Factor VIIa. Part Seven: Transfusion Medicine Platelet Storage and Transfusion. Platelet Transfusion in Infants and Children. Platelet Substitutes and Novel Methods of Platelet Preservation. Part Eight: Gene Therapy Gene Therapy for Platelet Disorders.
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