Platelet-Activating Factor Acetylhydrolases (PAF-AH): Volume 38

Platelet-Activating Factor Acetylhydrolases (PAF-AH): Volume 38

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This volume of The Enzymes summarizes the most important discoveries associated with a group of enzymes that play an important role in normal biological processes as presented and discussed by leaders authorities in the field.
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Product details

  • Hardback | 222 pages
  • 152 x 229 x 20.32mm | 540g
  • Academic Press Inc
  • San Diego, United States
  • English
  • 0128039086
  • 9780128039083

Table of contents

Overview of PAF Degrading Enzymes
Ken Karasawa and Keizo Inoue
Intracellular PAF Acetylhydrolase Type I
Mitsuharu Hattori and Hiroyuki Arai
Platelet-Activating Factor Acetyl Hydrolase and Brain Development
Gary D. Clark
Intracellular Platelet Activating Factor (PAF) Acetylhydrolase, Type II: A Unique Cellular Phospholipase A2 that Hydrolyzes Oxidatively-Modified Phospholipids
Nozomu Kono and Hiroyuki Ara
Trafficking and Oligomeric Regulation of Platelet-Activating Factor Acetylhydrolase Type II
Meghan M. Klems and Brian J. Bahnson
Plasma PAF-AH (PLA2G7): Biochemical Properties, Association with LDLs and HDLs, and Regulation of Expression
Diana M. Stafforini
Crystal Structure and Atomic Level Analysis of Plasma PAF-AH
Tara D. Gonzalez and Brian J. Bahnson
Naturally Occurring Missense Mutation in Plasma PAF-AH Among the Japanese Population
Ken Karasawa
Plasma PAFAH/PLA2G7 Genetic Variability, Cardiovascular Disease and Clinical Trials
Sonia Karabina and Ewa Ninio
Diverse Functions of Plasma PAF-AH in Tumorigenesis
Diana M. Stafforini
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About Fuyuhiko Tamanoi

Fuyu Tamanoi is a biochemist who has served on the UCLA School of Medicine and UCLA College faculty since he joined the Department of Microbiology, Immunology & Molecular Genetics in 1993. He became a full professor in 1997. Since 1996, he has been a Director of Signal Transduction Program Area at Jonsson Comprehensive Cancer Center. Dr. Tamanoi earned his B.S. and M.S. in Biochemistry at the University of Tokyo. He received PhD in Molecular Biology at Nagoya University in 1977. He was a postdoctoral fellow at Harvard Medical School, where he worked on bacteriophage DNA replication. From 1980 to 1985, he was a senior staff investigator at Cold Spring Harbor Laboratory, where he worked on adenovirus DNA replication. From 1985 to 1993, he was an Assistant Professor and then Associate Professor at the University of Chicago, where he initiated studies on lipid modification of the Ras family proteins. His laboratory research centers on signal transduction and signal transduction inhibitors. He is currently exploring ways to deliver signal transduction inhibitors using nanoparticles. Dr. Diana Stafforini works at the Huntsman Cancer Institute at the University of Utah School of Medicine. Professor Inoue works at the Teikyo University, School of Pharmacy, Japan.
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