Peptide, Protein and Enzyme Design: Volume 580

Peptide, Protein and Enzyme Design: Volume 580

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De Novo Enzyme Design, the newest volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume includes the design of metal binding maquettes, insertion of non-natural cofactors, Cu metallopeptides, non-covalent interactions in peptide assemblies, peptide binding and bundling, heteronuclear metalloenzymes, florinated peptides, De Novo imaging agents, and protein-protein interaction.
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Product details

  • Hardback | 684 pages
  • 152 x 229 x 38.1mm | 1,250g
  • Academic Press Inc
  • San Diego, United States
  • English
  • 0128053801
  • 9780128053805

Review quote

Praise for the Series: "Should be on the shelves of all libraries in the world as a whole collection." --Chemistry in Industry "The work most often consulted in the lab." --Enzymologia "The Methods in Enzymology series represents the gold-standard." --Neuroscience
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Table of contents

Chemical Post-Translational Modification with Designed Rhodium(II) Catalysts
Samuel C. Martin, Matthew B. Minus and Zachary T. Ball
Cell Binding Assays for Determining the Affinity of Protein-Protein Interactions: Technologies and Considerations
Sean Hunter and Jennifer Cochran
Protein and Antibody Engineering by Phage Display
Julia C. Frei and Jonathan R. Lai
Incorporation of Unnatural Amino Acids into Proteins Expressed in Mammalian Cells
Robert Serfling and Irene Coin
Method for Enzyme Design with Genetically Encoded Unnatural Amino Acids
Cheng Hu and Jiangyun Wang
Methods for Solving Highly Symmetric De Novo Designed Metalloproteins: Crystallographic Examination of a Novel Three Stranded Coiled Coil Structure Containing D-Amino Acids
Leela Ruckthong, Jeanne A. Stuckey and Vincent L. Pecoraro
SpyRings Declassified: A Blueprint for using Isopeptide-Mediated Cyclization to Enhance Enzyme Thermal Resilience
Christopher Schoene, S. Paul Bennett and Mark Howarth
Engineering and Application of LOV2-Based Photoswitches
Seth Parker Zimmerman, Brian Kuhlman and Hayretin Yumerefendi
Minimalist Design of Allosterically Regulated Protein Catalysts
Olga V. Makhlynets and Ivan V. Korendovych
Combining Design and Selection to Create Novel Protein-Peptide Interactions
Elizabeth B. Speltz, Nicholas Sawyer and Lynne Regan
Metal-Directed Design of Supramolecular Protein Assemblies
Jake B. Bailey, Rohit H. Subramanian, Lewis A. Churchfield and F. Akif Tezcan
Designing Fluorinated Proteins
E. Neil G. Marsh
Solid Phase Synthesis of Helically Folded Aromatic Oligoamides
Simon J. Dawson, Xiaobo Hu, Stijn Claerhout and Ivan Huc
Conformational Restriction of Peptides Using Dithiol Bis-Alkylation
Leila Peraro, Timothy R. Siegert and Joshua A. Kritzer
Engineering Short Pre-Organized Peptide Sequences for Metal Ion Coordination: Copper(II) a Case Study
Luis M. P. Lima and Olga Iranzo
De Novo Construction of Redox Active Proteins
C. C. Moser, M. M Sheehan, N. M. Ennist, G. Kodali, C. Bialas, M. T. Englander, B. M. Discher and P. L. Dutton
Design Strategies for Redox Active Metalloenzymes: Applications in Hydrogen Production
Rafael Alcala-Torano, Dayn Joseph Sommer, Zahra Bahrami Dizicheh and Giovanna Ghirlanda
Equilibrium Studies of Designed Metalloproteins
Brian R. Gibney
Reconstitution of Heme Enzymes with Artificial Metalloporphyrinoids
Koji Oohora and Takashi Hayashi
Creation of a Thermally Tolerant Peroxidase
Yoshihito Watanabe and Hiroshi Nakajima
Designing Covalently Linked Heterodimeric Four-Helix Bundles
Marco Chino, Linda Leone, Ornella Maglio and Angela Lombardi
Design of Heteronuclear Metalloenzymes
Ambika Bhagi-Damodaran,Parisa Hosseinzadeh, Evan Mirts, Julian Reed, Igor D. Petrik and Yi Lu
Periplasmic Screening for Artificial Metalloenzymes
Markus Jeschek, Sven Panke and Thomas R. Ward
De Novo Designed Imaging Agents Based on Lanthanide Peptides Complexes
Anna F. A. Peacock
Peptide Binding for Bio-Based Nanomaterials
Nicholas M. Bedford, Catherine Munro and Marc R. Knecht
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About Vincent L Pecoraro

John T. Groves Collegiate Professor of Chemistry, Department of Chemistry, University of Michigan, USA
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Review Text

Praise for the Series: "Should be on the shelves of all libraries in the world as a whole collection." --Chemistry in Industry "The work most often consulted in the lab." --Enzymologia "The Methods in Enzymology series represents the gold-standard." --Neuroscience
show more