Parkinson's Disease

Parkinson's Disease

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A team of internationally acknowledged authorities have contributed chapters to this volume on Parkinson's disease, which attempts to give a scholarly, detailed, comprehensive and well-referenced account of this ubiquitous disease of the central nervous system. It includes a historical account of the life and times of James Parkinson including his scientific achievements, contributions from the relevant neurosciences - functional neuroanatomy, clinical neurophysiology of the basal ganglia, neurochemistry, experimental psychology and neuropathology, as well as the experimental background to brain grafts. Also included is an up-to-date discussion on the latest clinical experience with transplant surgery. The clinical section covers aetiologies, epidemiology, clinical features and differential diagnoses, neuropsychiatric aspects, methods of assessment, the many facets of medical and surgical treatments, and concludes with an attempt to assess the present and future potential of research. This book should be of interest to neurologists, neurosurgeons, neuropathologists and neuropharmacologists.
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Product details

  • Hardback | 720 pages
  • Hodder Arnold
  • London, United Kingdom
  • English
  • 70 illus
  • 0412262207
  • 9780412262203

Table of contents

Part I The neurosciences: the functional anatomy of the basal ganglia, Keith E. Webster; neurophysiology of Parkinson's disease, C. David Marsden; the biochemistry of Parkinson's disease, Yves Agid, Merle Ruberg et al; the neuropharmacology of Parkinson's disease, Gavin P. Reynolds and Peter Riederer; experimental psychology - functions of different regions of the basal ganglia; pathology of Parkinson's disease - the importance of the Sustantia Nigra and Lewy Bodies, Lysia S. Forno; transplantation of dopamine cell suspensions to the dopamine-depleted neostriatum, Stephen B. Dunnett, Anders Bjorklund et al. Part 2 Clinical considerations: aetiology of Parkinson's disease, Donald B. Calne and Keith Burton; epidemiology of Parkison's disease, Paul M. McKeigue and Michael Marmot; natural history of the untreated pre-L-dopa disease, Margaret M. Hoehn; the classification of Parkinson's disease, Franz Gerstenbrand and Werner Poewe; clinical features, George Selby; the behavioural neurology of Parkinson's disease, Andrew J. Lees; post-encephalitic syndromes, Oliver W. Sacks; the differential diagnosis of Parkinson's disease, Roger Duvoisin; assessment and measurement, Johannes P.W.F. Lakke. Part 3 Therapy of Parkinson's disease: principles of medical treatment, Melvin D. Yahr; dopamine agonists in Parkinson's disease, Abraham N. Lieberman, Govindan Gopinathan et al; L-dopa induced dyskinesias, Harald L. Klawans, Anna Hitri et al; L-Dopa related motor fluctuations, Richard J. Hardie; surgical treatment in the L-dopa era, Hirotaro Narabayashi; physical treatments, Richard J. Godwin-Austen; current research, Gerald M. Stern.
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