The Pancreatic Beta Cell: Volume 95

The Pancreatic Beta Cell: Volume 95

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First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press.

The Series provides up-to-date information on vitamin and hormone research spanning data from molecular biology to the clinic. A volume can focus on a single molecule or on a disease that is related to vitamins or hormones. A hormone is interpreted broadly so that related substances, such as transmitters, cytokines, growth factors and others can be reviewed.

This volume focuses on the pancreatic beta cell.
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Product details

  • Hardback | 520 pages
  • 156 x 232 x 28mm | 959.99g
  • Academic Press Inc
  • San Diego, United States
  • English
  • 0128001747
  • 9780128001745

Table of contents

Metabolic Regulation of Insulin Secretion
Kevin Keane and Philip Newsholme
Proinsulin Entry and Transit through the Endoplasmic Reticulum in Pancreatic Beta Cells
Ming Liu, Jordan Wright, Huan Guo, Yi Xiong and Peter Arvan
Metabolism-Secretion Coupling and Mitochondrial Calcium Activities in Clonal Pancreatic Beta-Cells
Lukas N. Groschner, Muhammad Rizwan Alam and Wolfgang F. Graier
Metabolic Syndrome and Ionic Channels in Pancreatic Beta-Cells
Marcia Hiriart, Myrian Velasco, Carlos Larque and Carlos Manlio Diaz-Garcia
The Beta Cell Immunopeptidome
Nadine L. Dudek and Anthony W. Purcell
Autophagy and Pancreatic Beta Cells
Simona Mazza and Tania Maffucci
The Somatostatin Receptor in Human Pancreatic ss-Cells
Matthias Braun
Modulation of the Pancreatic Islet-Stress Axis as a Novel Potential Therapeutic Target in Diabetes Mellitus
Barbara Ludwig, Andreas Barthel, Andreas Reichel, Norman L. Block, Stefan Ludwig, Andrew V. Schally and Stefan R. Bornstein
Regenerative Medicine for Diabetes: Differentiation of Human Pluripotent Stem Cells into Functional ss Cells in Vitro and their Proposed Journey to Clinical Translation
Bipasha Bose, Kishore Reddy Katikireddy and Sudheer Shenoy
The Calcium-Sensing Receptor and ss-Cell Function
Paul E. Squires, Peter M. Jones, Mustafa Y.G. Younis and Claire E. Hills
Cellular Inhibitor of Apoptosis Protein-1 and Survival of Beta Cells Undergoing Endoplasmic Reticulum Stress
Pu Xia and Yanfei Qi
ss-Cell Responses to Nitric Oxide
Katarzyna A. Broniowska, Bryndon J. Oleson and John A. Corbett
Activated Protein C and its Potential Applications in prevention of islet ss Cell Damage and Diabetes
Meilang Xue and Christopher J. Jackson
Zinc and its Transporters, Pancreatic ss-Cells, and Insulin Metabolism
Liping Huang
The NOTCH Pathway in ss-Cell Growth and Differentiation
Yael Bar and Shimon Efrat
Roles of HNF1α and HNF4α in Pancreatic ss-Cells: Lessons from a Monogenic form of Diabetes (MODY)
Kazuya Yamagata
Role of the Mammalian Target of Rapamycin (mTOR) Complexes in Pancreatic Beta Cell Mass Regulation
Alberto Bartolome and Carlos Guillen
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About Gerald Litwack

Following a liberal arts education with a major in chemistry and biology at Hobart College, Gerald (Gerry) Litwack earned M.S. and PhD degrees in biochemistry from the University of Wisconsin, Madison where he served as a Lecturer in Enzymology before starting a postdoctoral fellowship from the National Foundation for Infantile Paralysis at the Biochemical Institute of the Sorbonne in Paris. His first academic position was assistant professor of biochemistry at Rutgers University where he started his work on hormone action for six years. During this period, he did a sabbatical at the University of California, Berkeley, where he concentrated on rapid enzyme kinetics. In 1960 he accepted an offer of an associate professorship at the University of Pennsylvania Graduate School of Medicine. In 1964, he was invited to be full professor of biochemistry at The Fels Institute for Cancer Research and Molecular Biology at Temple Medical School, simultaneously with a Career Development Award from the NIH, where he later was named Deputy Director of the Institute and the Laura H. Carnell Professor in biochemistry. Subsequently, he was given the Faculty Research Award. He co-discovered ligandin, later found to be in the family of glutathione S-transferases, enzymes that protect the body from carcinogens. In 1991, he moved to the Jefferson Medical College at Thomas Jefferson University as Professor of Biochemistry, Chair of the Department of Pharmacology and Deputy Director of the Kimmel Cancer Research Institute. Later, he became chair of the combined Department of Biochemistry and Molecular Pharmacology and concurrently held the position of Vice Dean for Research. In 2003, he moved to Los Angeles and from 2004-2006 was a Visiting Scholar at the University of California, Los Angeles, in the Department of Biological Chemistry of the Geffen School of Medicine and, in this period, wrote "Human Biochemistry and Disease" a volume of 1254 pages. In 2007, he moved to Scranton, Pennsylvania, as Founding Chair of Basic Sciences and Acting Associate Dean for Research to start a new medical school, The Commonwealth Medical College. Having completing his mission in 2010, he moved to The Institute for Regenerative Medicine, Texas A & M Health Science Center, as Professor of Biochemistry and Associate Director. Currently, he is retired and lives in North Hollywood, California, where he continues as an author and as Series Editor of Vitamins and Hormones. He is involved in writing another textbook and has written a first novel, "One-Eighty".
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