The Ovary

The Ovary

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This second edition of The Ovary incorporates the dramatic research developments regarding the ovarian life cycle within the past decade.
It looks at ovarian function from a detailed molecular and cellular level. The updated chapters, along with the new material, represent an unparalleled compilation of chapters relevant to contemporary ovarian physiology. The book is divided into 8 sections: The Ovarian Follicular Apparatus: Operational Characteristics; Oocyte Maturation and Ovulation; The Corpus Luteum; Putative Intraovarian Regulators; Cyclic Ovarian Cell Death; Novel Experimental Models; Human Ovarian Pathophysiology: Select Aspects; and Human Ovarian Surface Epithelium and Neoplasia.
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Product details

  • Hardback | 664 pages
  • 215.9 x 281.9 x 43.2mm | 2,199.95g
  • Academic Press Inc
  • San Diego, United States
  • English
  • 2nd edition
  • 0124445624
  • 9780124445628

Table of contents

Neural and Neurotrophic Control of Ovarian Development
Dynamics of Human Follicular Growth: Morphologic, Dynamic and Functional Aspects
Dynamics of Primate Follicular Growth: A Physiologic Perspective
Functional Consequences of Mutations and Polymorphisms in Gonadotropin and Gonadotropin Receptor Genes
The Regulation of Gonadotropin Receptor in the Ovary
Prostaglandin Biosynthesis and Action in the Ovary
Actions of Insulin IGF-I on sterol-metabolizing Gene Expression in Ovarian Cells
Intracellular Cholesterol Dynamics in Steroidogenic Cells
Regulation of Mammalian Oocyte Maturation
Oocyte-Granulosa Cell Interactions
Ovulation: An Inflammatory Cascade of Gene Expression
The Function and Regulation of Cell Populations Composing
The Corpus Luteum of the Ovarian Cycle
The Corpus Luteum of Pregnancy
Potential Role of Cytokines in Ovarian Physiology: The Case for Interleukin-1
Activin, Inhibin and Follistatin in Ovarian Physiology
GnRH as an Autocrine Regulator in the Human Ovary
Ovarian Angiogenesis
Apoptosis in Ovarian Development, Function and Failure
Reactive Oxygen Species and Ovarian Function
Follicle Selection in Mammalian Ovaries: Regulatory Mechanisms of Granulosa Cell Apoptosis during Follicular Atresia
Generation and Application of Ovarian Steroidogenic Cell Lines
The Application of Gene Ablation and Related Technologies to the Study of Ovarian Function
Bioinformatic Analysis of Ovarian Genes Using an Ovary-Specific Database
Human Ovarian Pathophysiology: Select Aspects
Gonadotropin Ovulation Induction
The Role of GnRH Antagonists in Supporting Ovarian Hyperstimulation
The Ovarian Factor in Assisted Reproductive Technology
Ovarian Function in Assisted Reproduction
Polycystic Ovary Syndrome
The Role of the Ovary in the Genesis of Hyperandrogenism
Luteal Dysfunction
Germ Cell Failure and Ovarian Resistance: Human Genes and Disorders
Ovarian Function and Survival of Patients with Cervical Carcinoma Treated with Radical Hysterectomy and Ovarian Transposition
Role of Mitochondria in the Aging Ovary
Development & Differentiation of Ovarian Surface Epithelium: Cues for the Basis of its Malignant Potential
Molecular Mechanisms of Ovarian Neoplastic Progression
Ovarian Carcinogenesis
The Role of X-Linked Inhibitor of Apoptosis Protein in Chemoresistant Ovarian Cancer
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Review Text

"The chapters are well written...The Ovary should be of great value to established scholars in the field because it conveniently reviews the developments of the past decade and will quickly bring them up to date. This handsome volume can be highly recommended. Each chapter is amply referenced, making this book a great resource for anyone with a detailed interest in the ovary."

"...a comprehensive reference and value for the money...more for those who are curious to enquire into the scientific basis of clinical medicine."
--David T. Baird, MB BChr, DSc, Professor Emeritus, University Department of Obstetrics and Gynaecology and Director ofo Contraceptive Development Network, Edinburgh, UK for Journal of Family Planning and Reproductive Health Care , Vol. 31, No. 1 June 20052004
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Review quote

"Each chapter is amply referenced, making this book a great resource for anyone with a detailed interest in the ovary."
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About Eli Y. Adashi

Dr. Leung is a Professor at UBC's Department of Obstetrics & Gynecology and is Associate Dean of Graduate and Postdoctoral Education in the Faculty of Medicine at UBC. Dr. Leung received his PhD from the University of Western Ontario. After post-doctoral training at the University of California at Los Angeles and the Laval University, he joined the University of British Columbia in 1982 as a faculty member. Dr. Leung has received a number of prestigious awards, including a Scholar Award and a Scientist Award from the Medical Research Council of Canada, and a Career Investigator Award from the Child and Family Research Institute. Dr. Leung has served on many national and international organizations, including as President of the Canadian Fertility and Andrology Society, Director of the Society for the Study of Reproduction, Director of the Ovarian Workshops in the USA, temporary advisor to the World Health Organization, Fellow of the Canadian Academy for Health Sciences, and Fellow of the Royal Society of Canada. Dr. Leung's research focuses on molecular aspects of hormone action in reproduction. Dr. Leung's publication record to date includes 365 papers, 26 abstracts, 22 book chapters and 5 monographs. Since his appointment at UBC, Dr. Leung has served as the research supervisor for 38 PhD students and 10 MSc students, 22 postdoctoral fellows and 26 visiting scientists. The major focus of Dr. Leung's research program is endocrine control of reproduction. Dr Leung's laboratory is best recognized for the cloning and characterization of the gene encoding the gonadotrop.
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