Origin and Evolution of Viruses

Origin and Evolution of Viruses

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Description

New viral diseases are emerging continuously. Viruses adapt to new environments at astounding rates. Genetic variability of viruses jeopardizes vaccine efficacy. For many viruses mutants resistant to antiviral agents or host immune responses arise readily, for example, with HIV and influenza. These variations are all of utmost importance for human and animal health as they have prevented us from controlling these epidemic pathogens. This book focuses on the mechanisms that viruses use to evolve, survive and cause disease in their hosts. Covering human, animal, plant and bacterial viruses, it provides both the basic foundations for the evolutionary dynamics of viruses and specific examples of emerging diseases.
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Product details

  • Hardback | 560 pages
  • 190 x 246 x 32mm | 1,338.09g
  • Academic Press Inc
  • San Diego, United States
  • English
  • 2nd edition
  • Approx. 110 illustrations (50 in full color); Illustrations, unspecified
  • 012374153X
  • 9780123741530
  • 2,118,083

Review quote

Review of the Previous Edition:

"...this book...is a detailed account of current thinking on virus evolution... Because of the diversity of subjects, this book gives an up to date picture of research in various fields of virology, and helps to tease out connections between these fields. The subjects covered are essential reading for virologists but also have direct relevance for molecular biologists, and indeed any researchers with interests in early evolution... This publication is highly recommended for its breadth of coverage and detailed treatments of the various subjects"
-TODAY'S LIFE SCIENCE (February 2001)
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Table of contents

Origins and widespread evolutionary significance of viruses; Nature and evolution of early replicons; Structure and evolution of viroids; Mutation, competition and selection as measured with small RNA molecules; Viral quasispecies, fitness variations and error;Phylogenetic analysis of viral sequences: principles and applications; Evolution of functional protein motifs in RNA viruses; Copying fidelity of viral and cellular polymerases; RNA interference and its evolutionary implications; Phage models of virus adaptation and evolution; Genomic analysis and evolution of large bacteriophages; Plant virus evolution: past, present and future; Mutant clouds and bottleneck events in plant virus evolution; Retrovirus evolution and pathogenesis; HIV population dynamics and drug treatments; The impact of rapid evolution of hepatitis viruses; Evolution of animal and human influenza viruses; Evolution and emergence of arboviruses; Parvovirus variation and evolution: impact on disease emergence; Genome diversity and evolution of human papillomaviruses; Poxvirus diversity and evolution; The molecular evolutionary history of the herpesviruses; Cellular functions involved in virual hypermutagenesis.
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About Esteban Domingo

Esteban Domingo studied chemistry and biochemistry at the University of Barcelona, Spain and spent postdoctoral stays at the University of California, Irvine and the University of Zurich. His main interests are the quasispecies structure of RNA viruses and the development of new antiviral strategies. He is presently Professor of Research of the Spanish Research Council (CSIC) at Centro de Biologia Molecular "Servero Ochoa" in Madrid.
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Review Text

Review of the previous edition:
"...this book...is a detailed account of current thinking on virus evolution... Because of the diversity of subjects, this book gives an up to date picture of research in various fields of virology, and helps to tease out connections between these fields. The subjects covered are essential reading for virologists but also have direct relevance for molecular biologists, and indeed any researchers with interests in early evolution... This publication is highly recommended for its breadth of coverage and detailed treatments of the various subjects"--TODAY'S LIFE SCIENCE (February 2001) Review of the previous edition:
"...this book...is a detailed account of current thinking on virus evolution... Because of the diversity of subjects, this book gives an up to date picture of research in various fields of virology, and helps to tease out connections between these fields. The subjects covered are essential reading for virologists but also have direct relevance for molecular biologists, and indeed any researchers with interests in early evolution... This publication is highly recommended for its breadth of coverage and detailed treatments of the various subjects"--TODAY'S LIFE SCIENCE (February 2001)
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Rating details

6 ratings
4.5 out of 5 stars
5 67% (4)
4 17% (1)
3 17% (1)
2 0% (0)
1 0% (0)
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