Obesity: Volume 91

Obesity: Volume 91

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First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology and enzyme mechanisms.

Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists and molecular biologists. Others interested in the structure and function of biologically active molecules like hormones and vitamins will, as always, turn to this series for comprehensive reviews by leading contributors to this and related disciplines.

This volume focuses on obesity.
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Product details

  • Hardback | 512 pages
  • 231.14 x 304.8 x 27.94mm | 566.99g
  • Academic Press Inc
  • San Diego, United States
  • English
  • New
  • 0124077668
  • 9780124077669

About Gerald Litwack

Following a liberal arts education with a major in chemistry and biology at Hobart College, Gerald (Gerry) Litwack earned M.S. and PhD degrees in biochemistry from the University of Wisconsin, Madison where he served as a Lecturer in Enzymology before starting a postdoctoral fellowship from the National Foundation for Infantile Paralysis at the Biochemical Institute of the Sorbonne in Paris. His first academic position was assistant professor of biochemistry at Rutgers University where he started his work on hormone action for six years. During this period, he did a sabbatical at the University of California, Berkeley, where he concentrated on rapid enzyme kinetics. In 1960 he accepted an offer of an associate professorship at the University of Pennsylvania Graduate School of Medicine. In 1964, he was invited to be full professor of biochemistry at The Fels Institute for Cancer Research and Molecular Biology at Temple Medical School, simultaneously with a Career Development Award from the NIH, where he later was named Deputy Director of the Institute and the Laura H. Carnell Professor in biochemistry. Subsequently, he was given the Faculty Research Award. He co-discovered ligandin, later found to be in the family of glutathione S-transferases, enzymes that protect the body from carcinogens. In 1991, he moved to the Jefferson Medical College at Thomas Jefferson University as Professor of Biochemistry, Chair of the Department of Pharmacology and Deputy Director of the Kimmel Cancer Research Institute. Later, he became chair of the combined Department of Biochemistry and Molecular Pharmacology and concurrently held the position of Vice Dean for Research. In 2003, he moved to Los Angeles and from 2004-2006 was a Visiting Scholar at the University of California, Los Angeles, in the Department of Biological Chemistry of the Geffen School of Medicine and, in this period, wrote "Human Biochemistry and Disease" a volume of 1254 pages. In 2007, he moved to Scranton, Pennsylvania, as Founding Chair of Basic Sciences and Acting Associate Dean for Research to start a new medical school, The Commonwealth Medical College. Having completing his mission in 2010, he moved to The Institute for Regenerative Medicine, Texas A & M Health Science Center, as Professor of Biochemistry and Associate Director. Currently, he is retired and lives in North Hollywood, California, where he continues as an author and as Series Editor of Vitamins and Hormones. He is involved in writing another textbook and has written a first novel, "One-Eighty".
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Table of contents

Hormonal Regulation of Lipogenesis
Laura L. Gathercole, Stuart A. Morgan and Jeremy W. Tomlinson

Genetic Determinants of Obesity and Related Vascular Diseases
Yaroslav Winter, Roman Sankowski and Tobias Back

Brd2 Gene Disruption Causes `Metabolically Healthy' Obesity: Epigenetic and Chromatin-Based Mechanisms that Uncouple Obesity from Type 2 Diabetes
Fangnian Wang, Jude T. Deeney and Gerald V. Denis

The TBC1D1 Gene: Structure, Function and Association with Obesity and Related Traits
Luca Fontanesi and Francesca Bertolini

Replication Initiator 1 (Repin1) In Adipose Tissue Function and Human Obesity
John T. Heiker and Nora Kloeting

Adipokines in Childhood Obesity
Gabriel Angel Martos-Moreno, Vicente Barrios, Julie A. Chowen and Jesus Argente

Gut Hormones and Obesity: Physiology and Therapies
Rebecca Scott, Tricia Tan and Stephen Bloom

Neuroinflammation in Overnutrition-Induced Diseases
Dongsheng Cai

P66shcA : Linking Mammalian Longevity with Obesity-Induced Insulin Resistance
Sofia Chiatamone Ranieri, Salvatore Fusco and Giovambattista Pani

The Emerging Role of Constitutive Androstane Receptor (CAR) and its Crosstalk with Liver X Receptors (LXRs) and Peroxisome Proliferator-Activated Receptor α (PPARα) in Lipid Metabolism
Lei Xiao, Jing Wang, Mengxi Jiang, Wen Xie and Yonggong Zhai

Lecithin Cholesterol Acyltransferase Deficiency Protects from Diet-Induced Insulin Resistance and Obesity - Novel Insights from Mouse Models
Dominic S. Ng

Sphingolipids in Lipid Microdomains and Obesity
Susumu Mitsutake and Yasuyuki Igarashi

Ghrelin: At the Interface of Obesity and Reward
Harriet Schellekens, Timothy G. Dinan, and John F. Cryan

Endocannabinoids and Obesity
Guoxun Chen and Zhen Pang

Lipocalin 13 Regulation of Glucose and Lipid Metabolism in Obesity
Yingjiang Zhou and Liangyou Rui

Sirtuin 1 Deacetylase: A Key Regulator of Hepatic Lipid Metabolism
Jongsook Kim Kemper, Sung-E Choi and Dong Hyun Kim

Protein Tyrosine Phosphatase 1B (PTP1B) and Obesity
Hyeongjin Cho

Nomilin as an Anti-Obesity and Anti-Hyperglycemic Agent Ryuichiro Sato
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