Nuclear Processes and Oncogenes

Nuclear Processes and Oncogenes

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The nuclear processes considered are not those involved in power plants or bomb testing, whose relationship with oncogenes is well known. Instead the 12 papers from the September 1990 symposium in Cambridge, Massachusetts, discuss the function and structure of nuclear proteins encoded by oncogenes and tumor suppressor genes. They also explore the relationship between the biochemical properties of such proteins and the regulation of transcription. Annotation copyright Book News, Inc. Portland, Or.
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Product details

  • Hardback | 210 pages
  • 152.4 x 228.6 x 17.78mm | 526.16g
  • Academic Press Inc
  • San Diego, United States
  • English
  • references, index
  • 0126390258
  • 9780126390254

Table of contents

Part 1 Nuclear oncogenes: oncogenes, tumor suppressor genes and the deregulation of cell growth - an overview, R.A. Weinberg; the functions of MYB and MYC, J.M. Bishop; transcriptional regulation of fos and jun, T. Curran, et al; transformation by v-erbA and v-erB modulation of differentiation and proliferation in erythroid progenitors, H. Beug, et al. Part 2 Nuclear tumor supressor genes: the p53 gene and gene product, R.S. Quartin, et al; the p53 gene in human cancer, S.J. Baker and B. Vogelstein; the retinoblastoma protein is regulated by the cdc2 kinase, Q. Hu, et al; cellular proteins that can interact specifically with the retinoblastoma susceptibility gene product, W.G. Kaelin, Jr., et al; the role of the WT1 tumor suppressor gene in the ediology of wilm, D.E. Housman; tumor. Part 3 Regulation of transcription: the serum response element - structure and function, R. Treisman; the mouse H19 gene - its structure and function in mouse development, S.M. Tilghman, et al; regulation of transcription in animal cells - factors and mechanisms, B.F. Pugh and R. Tjian.
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