Neurospora : Contributions of a Model Organism

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This book will serve as the definitive reference work on laboratory methods and the basic physiology, biochemistry, development, genetics, and molecular biology of Neurospora, a standard model filamentous fungus. Among the fungi, Neurospora is second only to yeast as a basic model organism, and there has been no standard guide to the organism until now. There is an annual Neurospora meeting that attracts about 600 workers annually, and the broader constituency for the book includes myocologists and the biotechnology community and a substantial number of geneticists, molecular, cell and developmental biologists interested in the questions for which Neourospora has been an important model more

Product details

  • Hardback | 346 pages
  • 187.96 x 264.16 x 27.94mm | 1,020.58g
  • Oxford University Press Inc
  • New York, United States
  • English
  • numerous halftones and line figures
  • 0195122364
  • 9780195122367

Table of contents

Preface; 1. A Brief History; 2. The Biology of Neurospora; 3. Genome and Mitosis; 4. Meiosis, Genetic Analysis, and Recombination Models; 5. Mutational, Biochemical, and Molecular Rationales; 6. Carbon Metabolism; 7. Nitrogen, Sulfur and Phosphate Metabolism; 8. Mitochondria; 9. DNA, RNA, and Protein Synthesis; 10. Stress; 11. Metabolic Investigations; 12. Growth and Form; 13. Cell Recognition, Population Biology and Evolution; 14. Genetic, Biochemical, and Molecular Techniques; Appendix A. Neurospora Genetic Nomenclature; Appendix B. Genetic Maps of N. crassashow more

Review quote

"Fungi have rarely been big-ticket items in scientific research in the US. . . . Many, however, consider fungi worthy of their own kingdom and all agree that they belong in the phylogenetic tree right next door to their closest relatives, the animals . . . Fungi can be great models for understanding how all eukaryotic cells work and, beyond that, they are uniquely important themselves. . . . Thus in all, Neurospora is a tremendous resource that is increasingly being exploited for basic research while also providing a road map for the fungi in general. . . . One needs a great compilation, at once informed and informative without being exhaustive and thereby exhausting. Organizing this, much less pulling it off, must really be a labor of love, an effort put forth by someone who has matured along with the system and can separate the spores from the agar. Fortunately, this field is blessed with more than one such grown-up, and one of them, Rowland Davis, has done it."--Cellshow more