Neuropeptide Y and Drug Development

Neuropeptide Y and Drug Development

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Description

Neuropeptide Y (NPY) is a ubiquitous and important messenger in the nervous system, with a wide range of physiological roles. It is involved in the body energy balance and is one of the most potent stimuli of food intake known. NPY also acts to regulate central and peripheral autonomic functions.

This book, written by academic and industrial experts in the field, links the most recent basic experimental knowledge about NPY and its receptors with areas of clinical importance.

This book will be of interest to those working in all areas of research affected by NPY, such as food intake and energy homeostasis, cardiovascular regulation and G-protein-coupled receptors, as well as those interested in the development of drugs as NPY targets.
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Product details

  • Hardback | 209 pages
  • 156 x 235.2 x 16.5mm | 522.53g
  • Academic Press Inc
  • San Diego, United States
  • English
  • 0123049903
  • 9780123049902

Back cover copy

Neuropeptide Y (NPY) is a ubiquitous and important messenger in the nervous system, with a wide range of physiological roles. It is involved in the body energy balance and is one of the most potent stimuli of food intake known. NPY also acts to regulate central and peripheral autonomic functions. This book, written by academic and industrial experts in the field, links the most recent basic experimental knowledge about NPY and its receptors with areas of clinical importance.
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Table of contents

Multiple Receptors and Multiple Actions Central Effects of Neuropeptide Y and Its Role in Obesity and Diabetes Neuropeptide Y in Sympathetic Nerves-Evidence for Y1 Receptor-Mediated Vascular Control Neuropeptide Y Receptor Types in Mammalian Brain Species Differences and Status in the Human Central Nervous System Extraordinary Structural Diversity of Neuropeptide Y Family Receptors The Importance of Various Parts of the Neuropeptide Y Molecule for Receptor Recognition Peptide Antagonists of Neuropeptide Y: Design, Structure, And Pharmacological Characterization SR 120819A or the First Generation of Orally-Active Neuropeptide Y1 Receptor Antagonists BIBP3226, A Potent and Selective Y1 Receptor Antagonist First Structure-Activity Studies and Localization of the Human Y1 Receptor Binding Site Discovery of Neuropeptide Y Receptor Antagonists
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