The Neuron

The Neuron : Cell and Molecular Biology

4.41 (29 ratings by Goodreads)
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Description

The third edition of The Neuron provides a comprehensive first course in the cell and molecular biology of nerve cells. The first part of the book covers the properties of the many newly discovered ion channels that have emerged through mapping of the genome. These channels shape the way a single neuron generates varied patterns of electrical activity. Next are covered the molecular mechanisms that convert electrical activity into the secretion of neurotransmitter hormones at synaptic junctions between neurons. The second part of the book covers the biochemical pathways that are linked to the action of neurotransmitters and that can alter the cellular properties of neurons or sensory cells which transduce information from the outside world into the electrical code used by neurons. The final section reviews our rapidly expanding knowledge of the molecular factors that induce an undifferentiated cell to become a neuron, and then guide it to form appropriate synaptic connections with its partners. This section also focuses on the role of ongoing experience and activity in shaping these connections, and finishes with an account of mechanisms thought to underlie the phenomena of learning and memory.show more

Product details

  • Paperback | 632 pages
  • 164 x 234 x 34mm | 1,102.22g
  • Oxford University Press Inc
  • New York, United States
  • English
  • Revised
  • 3rd Revised edition
  • 279 line & 35 halftone illus., 8-page 4-color insert
  • 0195145232
  • 9780195145236
  • 1,227,714

Review quote

"The text is impressively modern, with up-to date information on the trendiest areas of neurobiology . . . .the book is highly visual, with figures on virtually every page. The figures deserve special comment because they are a teacher's dream: simple and uncluttered, but conceptually powerful. Frankly, although the recommendation is often absurd, The Neuron is one of those books that really does belong on every shelf. "--Nature "The format of each chapter is ideally suited for easy, enjoyable, and almost effortless learning . . . This is a superbly written and well-illustrated text covering all of the major aspects of neuroscientific knowledge . . . every neuroscientist should keep a copy handy."--Journal of Psychiatry and Neuroscience "This is a first-rate textbook for a course in cellular neurobiology for upper-level university students. My colleagues and I took it out on a shakedown cruise with a class of 250 undergraduates. The wind really caught their sails, and we sped quickly through it in the ten weeks of the academic quarter. The students appreciated the consistent clarity and the uniformity of style. The illustrations are highly conceptual and were easily understood . . . The up-to-date presentation of many exciting recent findings is a great strength. General principles are illustrated with a useful blend of data from vertebrate and invertebrate systems."--William S Messer, Jr., in The Quarterly Review of Biology "An outstanding, easily readable, and quite up-to-date overview of fundamental neurobiology."--Canadian Journal of Neurological Sciences "The authors have produced an extremely well-integrated, highly readable, soft-cover volume which can introduce students of neuroscience into the field, and graduates into a refresher and review on recent developments in a most readable and logical progression, beginning with the cell, both neuron and glia, and progressing through the complexities of neuronal networks."--Journal of the Neurological Sciences "In spite of the overwhelming amount of information on all things neuronal, the authors have succeeded in providing in-depth coverage on many new discoveries in neuroscience and integrating the material into a readable text. ... The Neuron promises to be a very useful textbook ... and a helpful introductory guide for scientists just becoming interested in the nervous system."--The Quarterly Review of Biology "In spite of the overwhelming amount of information on all things neuronal, the authors have succeeded in providing in-depth coverage on many new discoveries in neuroscience and integrating the material into a readable text. ... The Neuron promises to be a very useful textbook ... and a helpfulintroductory guide for scientists just becoming interested in the nervous system."--The Quarterly Review of Biology "In spite of the overwhelming amount of information on all things neuronal, the authors have succeeded in providing in-depth coverage on many new discoveries in neuroscience and integrating the material into a readable text. ... The Neuron promises to be a very useful textbook ... and a helpful introductory guide for scientists just becoming interested in the nervous system."--The Quarterly Review of Biology "In spite of the overwhelming amount of information on all things neuronal, the authors have succeeded in providing in-depth coverage on many new discoveries in neuroscience and integrating the material into a readable text. ... The Neuron promises to be a very useful textbook ... and a helpfulintroductory guide for scientists just becoming interested in the nervous system."--The Quarterly Review of Biologyshow more

Table of contents

I. INTRODUCTION ; 1. Signaling in the Brain ; 2. Form and Function in Cells of the Brain ; II. ELECTRICAL PROPERTIES OF NEURONS ; 3. Electrical Signaling in Neurons ; 4. Membrane Ion Channels and Ion Currents ; 5. Ion Channels are Membrane Proteins ; 6. Ion Channels, Membrane Ion Currents, and the Action Potential ; 7. Diversity in the Structure and Function of Ion Channels ; III. INTERCELLULAR COMMUNICATION ; 8. How Neurons Communicate: Gap Junctions and Neurosecretion ; 9. Synaptic Release of Neurotransmitters ; 10. Neurotransmitters and Neurohormones ; 11. Receptors and Transduction Mechanisms I: Receptors Coupled Directly to Ion Channels ; 12. Receptors and Transduction Mechanisms II: Indirectly Coupled Receptor/Ion Channel Systems ; 13. Neuromodulation: Mechanisms of Induced Changes in the Electrical Behavior of Nerve Cells ; 14. Sensory Receptors ; IV. BEHAVIOR AND PLASTICITY ; 15. The Birth and Death of a Neuron ; 16. Neuronal Growth and Trophic Factors ; 17. Adhesion Molecules and Axon Pathfinding ; 18. Formation, Maintenance, and Plasticity ; 19. Neural Networks and Behavior ; 20. Learning and Memoryshow more

Rating details

29 ratings
4.41 out of 5 stars
5 59% (17)
4 31% (9)
3 7% (2)
2 0% (0)
1 3% (1)
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