Neural Development and Stem Cells

Neural Development and Stem Cells

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This extensively expanded and updated edition reflects the enormous increase in our knowledge of the development of the nervous system. Working from a new understanding that the regionalization of stem cells occurs early in development and that this bias appears to persist even after prolonged culture, Dr. Rao has added additional chapters on olfactory epithelial stem cells and retinal stem cells, both of which differ in their properties from ventricular zone and subventricular zone-derived neural stem cells. A new chapter on cell death summarizes the important changes in the death pathway that occurs as stem cells mature. Special attention is paid to the derivation of neural cells from embryonic stem cells. Authoritative and up-to-date, "Neural Development and Stem Cells, Second Edition" provides neuroscientists with a handy guide to stem cells in the nervous system, tracing with great clarity the development of stem cells from differentiation to neurons, astrocytes, and oligodendrocytes.
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Product details

  • Hardback | 468 pages
  • 186 x 260 x 32mm | 1,478.73g
  • Totowa, NJ, United States
  • English
  • Revised
  • 2nd Revised edition
  • 84 black & white illustrations
  • 1588294811
  • 9781588294814

Review quote

.,."provides a fascinating insight about an exciting and emereging field of neuroscience." -Journal of Chemical Neuroanatomy "This book is a well-balanced amalgamation of background knowledge, as well as valuable information for the scientists working in the dynamic area of stem cell research." -Journal of Chemical Neuroanatomy From Reviews of the First Edition... .,."Mahendra Rao is to be commended on organizing such an outstanding book in one of the most rapidly growing areas of basic and applied neuroscience research...a seminal book that will prove valuable to the neuroscience community over the coming years." -Journal of Molecular Neuroscience .,."a valuable tool for neurobiologists to unravel this complex field..." -Drug Discovery Today .,."a surprisingly readable book...also very informative. Any interested clinician that wants a broad overview of the field should consult this text; so should anyone considering research in this exciting and rapidly developing field." -British Journal of Neurosurgery
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Table of contents

Defining Neural Stem Cells and Their Role in Normal Development of the Nervous System Sally Temple Neural Stem Cells in the Adult Brain: Implications of Their Glial Characteristics Daniel A. Lim and Arturo Alvarez-Buylla Cellular and Molecular Properties of Multipotent Neural Stem Cells Throughout Ontogeny Larysa Halyna Pevny Multipotent Stem Cells in the Embryonic Nervous System Ali Jalali, Michael Bonaguidi, Caitilin Hammill, and John A. Kessler Regulation of Neural Stem Cell Death Rizwan S. Akhtar and Kevin A. Roth Neuronal Progenitor Cells of the Mammalian Neonatal Anterior Subventricular Zone Douglas L. Falls and Marla B. Luskin Glial Restricted Precursors Mark Noble and Margot Mayer-Proschel PNS Precursor Cells in Development and Cancer Houman D. Hemmati, Tanya A. Moreno, and Marianne Bronner-Fraser Stem Cells of the Adult Olfactory Epithelium James E. Schwob and Woochan Jang Retinal Stem Cells Ani V. Das, Jackson James, Sreekumaran Edakkot, and Iqbal Ahmed Transdifferentiation in the Nervous System Ying Liu and Mahendra S. Rao Neural Progenitor Cells of the Adult Human Brain Steven A. Goldman ES Cells and Neurogenesis Robin L. Wesselschmidt and John W. McDondald Mobilizing of Neural Precursers in the Adult Central Nervous System Theo D. Palmer and Fred H. Gage Neural Stem Cells and Transplant Therapy: Intrinsic Programs and Clinical Applications Jaime Imitola and Evan Y. Snyder Appendix A: Neural Stem Cell Companies Appendix B: Stem Cells and Transplants Appendix C: Patents and Stem Cells Appendix D: Stem Cells and US Federal Guidelines
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