Nervous and Mental Disease Monographs Volume 29-31

Nervous and Mental Disease Monographs Volume 29-31

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This historic book may have numerous typos and missing text. Purchasers can usually download a free scanned copy of the original book (without typos) from the publisher. Not indexed. Not illustrated. 1919 edition. Excerpt: ... criticisms of the Abderhalden reaction, in spite of the recognition of the gross chemical interest, put one justly on guard against its pretended specificity towards the extracts of organs employed. I will then consider that the new investigations are not entirely conclusive relative to the existence of an endocrine factor, based solely on the Abderhalden reaction. The physiological method advocated by Gley in his report for judging of the functional capacity of the affected organ consists of injecting into animals the altered tissue in order to see if it still manifests the physiological properties of normal tissue. A priori, this-method seems of value, and, as Gley says, "this type of study seems to recommend itself in a general way to pathologists. The anatomo-pathological research which allows certain lesions to be authenticated should be amplified." And as an example he has cited his experiences with the cardio-vascular action of adrenal extract from thyroidectomized dogs compared with that obtained from normal canine glands. He did not note any difierence. Porak, who has followed this route, has arrived at unexpected results. Suprarenal extracts obtained under conditions of activity clearly greater than normal have given cardio-vascular reactions of less intensity than those that were obtained under normal conditions. As the cardio-vascular effect is proportionate to the richness in adrenalin one must conclude that not only is the richness in adrenalin of the suprarenals not in proportion to their activity, but that taken at a given moment they are less charged with adrenalin than are less active suprarenal glands. 81 C. J. Parhon et Gr. Odobesco, Encephale, 10 juin, 1914, pp. 489-582. 82 H. de Waele, Soc. de...show more

Product details

  • Paperback | 156 pages
  • 189 x 246 x 8mm | 290g
  • Rarebooksclub.com
  • United States
  • English
  • black & white illustrations
  • 123697994X
  • 9781236979940