Myocarditis
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Myocarditis : From Bench to Bedside

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Leslie T. Cooper, Jr., MD, and a panel of leading clinical and scientific experts comprehensively review both advances in basic scientific understanding and current clinical knowledge of inflammatory heart disease. On the clinical side they discuss the diagnosis, prognosis, and treatment of nonspecific and specific myocarditis in separate chapters devoted to such major idiopathic clinical entities as cardiac sarcoidosis, giant cell myocarditis, eosinophilic myocarditis, Chagas disease, rheumatic fever, and human immunodeficiency virus-related cardiomyopathy. Research articles complete the picture with discussions of the role of apoptosis in viral myocarditis, rat and mouse models of autoimmune giant cell and lymphocytic myocarditis, and the latest available data on enteroviral proteases and cardiomyopathy.show more

Product details

  • Hardback | 621 pages
  • 184 x 258 x 34mm | 1,741.81g
  • Humana Press Inc.
  • Totowa, NJ, United States
  • English
  • 2003 ed.
  • 156 black & white illustrations, 69 colour illustrations, biography
  • 158829112X
  • 9781588291127

Back cover copy

Myocarditis was last critically surveyed nearly a decade ago. During that time, our knowledge of viral-induced myocardial injury, autoimmune pathways in the heart, and the clinical treatment of myocarditis has advanced significantly. In Myocarditis: From Bench to Bedside, Leslie T. Cooper, Jr., md, has assembled a panel of leading clinical and scientific experts to comprehensively review this new knowledge, highlighting advances in both our basic scientific understanding and our current clinical knowledge of inflammatory heart disease. Topics covered span many disciplines, from the genetics of cardiotropic viral virulence to clinical epidemiology and treatment. On the clinical side the diagnosis, prognosis, and management of both nonspecific and specific myocarditis are extensively discussed in separate chapters devoted to such major idiopathic clinical entities as cardiac sarcoidosis, giant cell myocarditis, eosinophilic myocarditis, Chagas disease, rheumatic fever, and human immunodeficiency virus-related cardiomyopathy. Research articles complete the picture with discussions of the role of apoptosis in viral myocarditis, rat and mouse models of autoimmune giant cell and lymphocytic myocarditis, and the latest available data on enteroviral proteases and cardiomyopathy. Cutting-edge molecular methods of viral genome detection and both invasive and noninvasive diagnostic methods for viral and autoimmune myocarditis are also presented. Multidisciplinary, state-of-the-art, and richly illustrated, Myocarditis: From Bench to Bedside is the first book to cover the entire spectrum of myocarditis from basic research to bedside medicine, providing today's researchers and clinicians a platform for understanding these diseases and today's significantly improved treatments for congestive heart failure, arrhythmias, and premature cardiovascular death.show more

Review quote

"Perusal of this book shows that myocarditis is a very complex disease. There are various pathogenic mechanisms which are important in different patients. Much work remains to be done. This is an excellent book to review what we know at this time. This is a well-referenced book with more than 100 references and many chapters. There are 43 color plates and each chapter includes a short outline and an introductory and a concluding paragraph."-Doody's Health Sciences Book Review Journal "...reaches its editor's goal to "cover the entire spectrum of myocarditis from basic research to bedside medicine" and "to foster exchange of new ideas between basic and clinical investigators." This multiauthored book contains a large amount of important information and can serve both as a reference and as an account of research in progress...The book is clearly written thoroughly referenced, and well organized, with highlighted headings. It is also well illustrated...I highly recommend this authoritative and very readable book. It is a valuable resource for any physician or scientist seeking to understand myocarditis." - NEW ENGLAND JOURNAL of MEDICINEshow more

Table of contents

Introduction and Historical Perspective on Experimental Myocarditis Charles J. Gauntt The Primary Viruses of Myocarditis Kyung-Soo Kim, Katja Hofling, Steven D. Carson, Nora M. Chapman, and Steven Tracy Cellular Autoimmunity in Myocarditis Sally A. Huber Humoral Immune Response in Viral Myocarditis Bernhard Maisch and Arsen D. Ristic Cytokines in Experimental Myocarditis Akira Matsumori Nitric Oxide Signaling in Myocarditis Joshua M. Hare and Charles J. Lowenstein Life and Death Signaling Pathways in CVB3-Induced Myocarditis Bobby Yanagawa, Mitra Esfandiarei, Chris Carthy, Paul Cheung, Honglin Luo, David Granville, Decheng Yang, Jonathan Choy, Amy Lui, Darya Dabiri, Janet E. Wilson, Aikun Wang, Mary Zhang, Simon Sinn, Bruce M. McManus, Kevin Wei, Ismail Laher Animal Models of Autoimmune Myocarditis Makoto Kodama, Yuji Okura, Yoshifusa Aizawa, and Tohru Izumi Progression of Myocarditis to Dilated Cardiomyopathy: Role of the Adrenergic System and Myocardial Catecholamines Petar M. Seferovic, Arsen D. Ristic, and Ruzica Maksimovic Pathogenesis of Enteroviral Cardiomyopathy: Interaction of Viral Proteins With Infected Myocytes Dingding Xiong, Cornel Badorff, and Kirk U. Knowlton Introduction to Clinical Myocarditis G. William Dec Use of Cardiac Biomarkers for Detection of Myocarditis Allan S. Jaffe Molecular Biologic Detection of Virus Infection in Myocarditis and Dilated Cardiomyopathy Karin Klingel Pathology of Human Myocarditis Gerald J. Berry and Kristen A. Atkins Endomyocardial Biopsy in Myocarditis Joseph G. Murphy, and Robert P. Frantz Treatment of Lymphocytic Myocarditis Jay W. Mason Idiopathic Giant Cell Myocarditis Leslie T. Cooper, Jr. Cardiac Sarcoidosis Leslie T. Cooper,Jr. The Eosinophil in Cardiac Disease Lambert A. Wu, Leslie T. Cooper, Jr., Gail M. Kephart, and Gerald J. Gleich Chagas Heart Disease James M. Hagar and Shahbudin H. Rahimtoola Cardiac Involvement in Acute Rheumatic Fever Jagat Narula, Ragavendra Baliga, Navneet Narula, Prem Chopra, and Y. Chandrashekhar Myocarditis Associated With Human Immunodeficiency Virus Infection and Acquired Immunodeficiency Syndrome Lyle J. Olson Childhood Myocarditis and Dilated Cardiomyopathy Neil E. Bowles and Jeffrey A. Towbin Peripartum Cardiomyopathy Joseph G. Murphy Indexshow more