Myasthenia Gravis and Related Disorders

Myasthenia Gravis and Related Disorders

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Description

An international panel of expert clinicians and leading scientists comprehensively review the clinical and basic science of this disease and its relatives, including acquired neuromytonia and Lambert-Eaton syndrome. For the clinician, the book describes the wide range of signs and symptoms that make these diseases difficult to diagnose, review in depth the available diagnostic methods and their limitations, offer practical treatment recommendations based on years of experience, and discuss several promising treatments now emerging. For the basic scientist, the text illuminates neuromuscular structure and function, describes in detail the acetylcholine receptor (the central target of pathology in myasthenia gravis), and illuminates the autoimmune pathogenesis.show more

Product details

  • Hardback | 400 pages
  • 154.9 x 231.1 x 27.9mm | 739.37g
  • Humana Press Inc.
  • Totowa, NJ, United States
  • English
  • 0
  • 1588290581
  • 9781588290588

Review quote

The book covers the physiology of the neuromuscular junction and of the ACR structure with detailed illustrations. There are extensive dissertations on the immunopathogenesis of myasthenia gravis, on the different immunogenetic properties of different thymona types, and finally on the different clinical presentations and therapeutic options. An entire chapter is devoted to when thymectomy is necessary and how it is performed. The chapter on myasthenia gravis crisis is concise and informative. This is a well organized, comprehensive book with abundant up-to-date references. It belongs in the library of any neurologist involved in the care of neuromuscular junction disorders. - Doody's Health Sciences Book Review Journal ...a well rounded book. I think that neurologists in training and general neurologists wanting a refresher course could do a lot worse then read this text. I would certainly recommend it. Brain: A Journal of Neurology Primarily this book will appeal to neurologists, clinical neurophysiologists, and neuroanaesthetists who will find it useful for their everyday clinical practice; researchers of neuromuscular junction disorders will also find the book interesting. This book is an up-to-date and valuable source of information on myasthenia and related disorders. - The Lancet Generally, the chapters are well-written, illustrations are appropriate, and the twenty-first century well represented in the references. The book is useful and up-to-date summary of all aspects of MG and its related disorders. - Muscle & Nerve This book is strongly recommended to clinicians and researchers dealing with neuromuscular disorders (and to thoracic surgeons performing thymectomy). - Journal of Neurology, Neurosurgery, and Psychiatryshow more

Table of contents

Neuromuscular Junction Physiology and Pathophysiology. Acetylcholine Receptor Structure. Immunopathogenesis of Myasthenia Gravis. Clinical Presentation and Epidemiology of Myasthenia Gravis. Ocular Myasthenia. Thymoma-Associated Myasthenia Gravis. Electrodiagnosis of Neuromuscular Junction Disorders. Specific Antibodies in the Diagnosis and Management of Autoimmune Disorders of Neuromuscular Transmission and Related Diseases. Treatment of Myasthenia Gravis. Neurocritical Care of Myasthenia Gravis Crisis. Thymectomy. Lambert-Eaton Syndrome. Acquired Neuromyotonia. Congenital Myasthenic Syndromes. Toxic Neuromuscular Transmission Disorders. Psychological and Social Consequences of Myasthenia Gravis. Appendix: Myasthenia Gravis Foundation of America Recommendations for Clinical Research Standards. Index.show more

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