This concise, abundantly illustrated text provides a complete overview of multiple sclerosis for the internist, general neurologist and therapist. Including recent research findings in genetics, immunology and pathophysiology, the authors provide reliable and up-to-date guidance on the epidemiology, diagnosis, prognosis and treatment of MS. Of particular interest to neuroscientists and neurologists will be the reviews of experimental models of MS, pathology of the demyelinated plaque, HLA associations and the role of immune mechanisms. Environmental and geographical factors in the etiology of MS are examined, including the possible role of infectious agents. The clinical sections of the book include discussion of neurological, sexual, psychological and cognitive disturbances. Diagnostic criteria are reviewed, and rehabilitation measures are given special attention.
- Electronic book text
- 11 May 2012
- CAMBRIDGE UNIVERSITY PRESS
- Cambridge University Press (Virtual Publishing)
- Cambridge, United Kingdom
- 55 b/w illus. 2 colour illus.
Table of contents
Part I. General Aspects: 1. Historical perspective; 2. Pathology and experimental models; 3. Genetics and immunology; 4. Epidemiology; 5. Pathogenesis; 6. Pathophysiology of impaired neural transmission; Part II. Clinical Aspects: 7. Symptomatology; 8. Diagnosis; 9. Disease course; 10. Prognosis; 11. Differential diagnosis; 12. Assessment of performance, ability, and disability; Part III. Management and Therapy: 13. Symptomatic treatment and nutrition; 14. Therapy; Appendix: Assessment scales.
'... no doubt this book will stand out as useful for neurologists (juniors and seniors), therapists (especially physiotherapists) and basic scientists who want to find a reference book upon MS.' European Neurology 'The text is generally easy and enjoyable to read and gives a goof overview of each topic. An impressive list of references is provided. In conclusion, this is an important book which gives an informative overview of many aspects of MS.' The International MS Journal