Multiple Sclerosis

Multiple Sclerosis : A Mechanistic View

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Multiple Sclerosis: A Mechanistic View provides a unique view of the pathophysiology of multiple sclerosis (MS) and related disorders. As the only book on the market to focus on the mechanisms of MS rather than focusing on the clinical features and treatment of the disease, it describes the role of genetic and environmental factors in the pathogenesis of MS, the role of specific cells in the pathophysiology of the disease, and the pathophysiology of inflammatory and neurodegenerative disorders related to MS.

The book provides discussion of neurodegeneration and neuroregeneration, two critical emerging areas of research, as well as detailed discussion of the mechanisms of action of the approved and investigational drugs for treatment of MS and the emerging role of magnetic resonance spectroscopy (MRI) in investigations into MS.

It is the only book on the market to offer comprehensive coverage of the known mechanisms of MS and related diseases, and contains contributions from physicians and researchers who are worldwide experts in the field of study.

Focuses on the pathophysiologic mechanisms of multiple sclerosis and the mechanisms of action in agents for the treatment of MSDiscusses the roles of neurodegeneration and neuroregeneration in MS and related diseasesAuthored and edited by international leaders in the field of MS research
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Product details

  • Electronic book text | 508 pages
  • 152 x 229mm
  • Academic Press Inc
  • Oxford, United Kingdom
  • English
  • 0128010053
  • 9780128010051

Table of contents

Clinical manifestations of multiple sclerosis: An overviewNovel Therapies for Multiple Sclerosis: A Mechanistic ViewRole of B cells in the pathogenesis of MS: Mechanisms of actionRole of CD4+ T cells in the pathophysiology of MSGM-CSF in Central Nervous System AutoimmunityRole of cytokine-mediated crosstalk between T cells and non-immune cells in the pathophysiology of multiple sclerosisVitamin D: role in pathogenesis of Multiple SclerosisRole of genetic factors in pathogenesis of MSNeuropathology of multiple sclerosisPathophysiology of acute disseminated encephalomyelitisPathophysiology of experimental autoimmune encephalomyelitisPathophysiology of optic neuritisNeurodegeneration and Remyelination in Multiple SclerosisMechanisms of action of Glatiramer Acetate in the treatment of multiple sclerosisMechanism of Action of Interferon Beta in Treatment of Multiple SclerosisMechanisms of blood brain barrier disintegration in the pathophysiology of MSMechanisms and potentials of Stem Cells in the treatment of Multiple Sclerosis: The unpaved pathRole of neuroimaging in MSPathophysiology of Lymphatic Drainage of the Central Nervous System. Implications for the Pathophysiology of Multiple Sclerosis
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