Mouse Genetics

Mouse Genetics : Concepts and Applications

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Description

As nearly all human genes are present in the mouse genome, a growing number of biomedical researchers are finding they need to use the mouse as an experimental organism. This book fills a need for a single source covering the field of mouse breeding and genetics at a level of detail sufficient for pursuing independent investigations. A convenient compendium of practical information for the mouse genetics community as well as molecular biologists who use mouse models.show more

Product details

  • Hardback | 376 pages
  • 160 x 233.7 x 27.9mm | 612.36g
  • Oxford University Press Inc
  • New York, United States
  • English
  • New.
  • frontispiece, halftones, line drawings, tables
  • 0195075544
  • 9780195075540

Review quote

"Mapping the human genome and identifying genes that contribute to susceptibility and resistance to disease are currently major preoccupations in biomedical science. The foundations for much of this sophisticated field of research were established in the mouse . . . . Lee Silver in a pleasing and easy style presents a unique synthesis of modern molecular genetics and the biology of the laboratory mouse . . . . Provides exciting reading for the student and continuing education for the more applied worker . . . . An exciting introduction to the comprehensive biology that is involved in the intriguing mysteries of the evolutionary process." --Science"Students and researchers involved in mouse genetic research will find Silver's book a welcome addition to their shelves." --Choiceshow more

Table of contents

1. An introduction to mice ; 2. Town mouse, country mouse ; 3. Laboratory mice ; 4. Reproduction and breeding ; 5. The mouse genome ; 6. Mutagenesis and transgenesis ; 7. Mapping in the mouse: An overview ; 8. Genetic markers ; 9. Classical linkage analysis and mapping panels ; 10. Non-breeding mapping strategies ; Appendices ; A. Suppliers of mice ; B. Computational tools and electronic databases ; C. Source materials for further reading ; D. Statistics ; E. Glossaryshow more

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