The Mouse in Biomedical Research: Volume 3

The Mouse in Biomedical Research: Volume 3 : Normative Biology, Husbandry, and Models

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Normative Biology, Husbandry, and Models, the third volume in the four volume set, The Mouse in Biomedical Research, encompasses 23 chapters whose contents provide a broad overview on the laboratory mouse's normative biology, husbandry, and its use as a model in biomedical research. This consists of chapters on behavior, physiology, reproductive physiology, anatomy, endocrinology, hematology, and clinical chemistry. Other chapters cover management, as well as nutrition, gnotobiotics and disease surveillance. There are also individual chapters describing the mouse as a model for the study of aging, eye research, neurodegenerative diseases, convulsive disorders, diabetes, and cardiovascular and skin diseases. Chapters on imaging techniques and the use of the mouse in assays of biological products are also included.
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Product details

  • Hardback | 816 pages
  • 220 x 287 x 48mm | 2,119.97g
  • Academic Press Inc
  • San Diego, United States
  • English
  • 2nd edition
  • Approx. 210 illustrations; Illustrations, unspecified
  • 0123694574
  • 9780123694577
  • 2,172,453

Table of contents

Chapter 1: Gross Anatomy

Chapter 2: Mouse Physiology

Chapter 3: Reproductive Biology of the Laboratory Mouse

Chapter 4: Endocrinology: Bone as a Target Tissue for Hormonal Regulation

Chapter 5: Hematology of the Laboratory Mouse

Chapter 6: Clinical Chemistry of the Laboratory Mouse

Management, Techniques, and Husbandry

Chapter 7: Gnotobiotics

Chapter 8: Management and Design: Breeding Facilities

Chapter 9: Design and Management of Research Facilities for Mice

Chapter 10: Nutrition

Chapter 11: Health Delivery and Quality Assurance Programs for Mice

Chapter 12: Environmental and Equipment Monitoring

Chapter 13: Biomethodology and Surgical Techniques

Chapter 14: In-Vivo Whole-Body Imaging of the Laboratory Mouse

Use of Mice in Biomedical Research

Chapter 15: Behavioral Testing

Chapter 16: Cardiovascular Disease: Mouse Models of Atherosclerosis

Chapter 17: Convulsive Disorders

Chapter 18: Eye Research

Chapter 19: Genetic Analysis of Rodent Obesity and Diabetes

Chapter 20: Mouse Models in Aging Research

Chapter 21: Mouse Models of Inherited Human Neurodegenerative Disease

Chapter 22: Mouse Skin Ectodermal Organs

Chapter 23: Quality Control Testing of Biologics

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About Fred W. Quimby

James G. Fox, DVM, MS, DACLAM, is a Professor and Director of the Division of Comparative Medicine and a Professor in the Division of Biological Engineering at the Massachusetts Institute of Technology. He is also an Adjunct Professor at Tufts University School of Veterinary Medicine and the University of Pennsylvania, School of Veterinary Medicine. He is a Diplomate and a past president of the American College of Laboratory Animal Medicine, past president of the Massachusetts Society of Medical Research, past chairman of AAALAC Council, and past chairman of the NCCR/NIH Comparative Medicine Study Section. He also is an elected fellow of the Infectious Disease Society of America. Professor Fox is the author of over 490 articles, 80 chapters, 3 patents and has edited and authored 13 texts in the field of in vivo model development and comparative medicine.
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