Molecular and Cellular Biophysics
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Molecular and Cellular Biophysics

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Description

From quantum theory to statistical mechanics, the methodologies of physics are often used to explain some of life's most complex biological problems. Exploring this challenging yet fascinating area of study, Molecular and Cellular Biophysics covers both molecular and cellular structures as well as the biophysical processes that occur in these structures. Designed for advanced undergraduate and beginning graduate students in biophysics courses, this textbook features a quantitative approach that avoids being too abstract in its presentation. Logically organized from small-scale (molecular) to large-scale (cellular) systems, the text first defines life, discussing the scientific controversies between mechanists and vitalists, the characteristics of living things, and the evolution of life. It then delves into molecular structures, including nucleic acids, DNA, RNA, interatomic interactions, and hydrogen bonds. After looking at these smaller systems, the author probes the larger cellular structures. He examines the cytoplasm, the cytoskeleton, chromosomes, mitochondria, motor proteins, and more. The book concludes with discussions on biophysical processes, including oxidative phosphorylation, diffusion, bioenergetics, conformational transitions in proteins, vesicle transport, subcellular structure formation, and cell division.show more

Product details

  • Hardback | 544 pages
  • 167.64 x 236.22 x 33.02mm | 861.82g
  • Taylor & Francis Inc
  • Chapman & Hall/CRC
  • Boca Raton, FL, United States
  • English
  • 216 black & white illustrations, 10 colour illustrations, 42 black & white tables
  • 1584886757
  • 9781584886754
  • 1,834,008

Table of contents

WHAT IS LIFE? Hierarchical Organization of Knowledge General Characteristics of Living Systems Artificial Life Biological Information, Information Processing, and Signaling Origin of Life Emergence, Intelligence, and Consciousness WHAT ARE THE MOLECULES OF LIFE? Nucleic Acids, DNA, RNA Generalized Ester Bonds Directionality of Chemical Bonds Types of Interatomic Interactions The Hydrogen Bonds and Hydrophobic Interactions Amphipatic Molecules in Water Environments Structure of Proteins Structure of Nucleic Acids WHAT IS A BIOLOGICAL CELL? Cytoplasm Cytoskeleton Tubulin Isotype Homology Modeling Anisotropic Elastic Properties of Microtubules Centrioles, Basal Bodies, Cilia, and Flagella Networks and Meshworks of Protein Filaments, Stress Fibers, and Tensegrity Cell Nucleus and Chromosomes Mitochondria and Proton Pumps: Energy Generation and Utilization in the Cell Cytochrome Oxidase Enzymes Membranes and Vesicles Motor Proteins and Their Role in Cellular Processes Directed Binding as a Model of Kinesin Walk Other Structures Large Polar Molecules WHAT ARE LIFE PROCESSES? Oxidative Phosphorylation Diffusion Processes Proton Transport and Bioenergetics Electronic and Ionic Conductivities of Microtubules and Actin Filaments Mechanisms of Exciton Energy Transfer in Scheibe Aggregates Conformational Transitions in Proteins Vesicle Transport and Molecular Motors Muscle Contraction Subcellular Structure Formation Cell Division GLOSSARY INDEX Questions, Problems, and References appear at the end of each chapter.show more

About Jack A. Tuszynski

University of Alberta, Edmonton, Canadashow more