Molecular and Cellular Aspects of Basement Membranes

Molecular and Cellular Aspects of Basement Membranes

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This volume is part of the "Cell Biology" series. It represents comprehensive treatment of a special field in extracellular matrix research which has undergone rapid progress in the past 20 years. Major topics discussed include the composition of basement membranes and their organization into extracellular matrices, the structural analysis of the various components of the basement membrane, and the role of basement membranes in cell-matrix interactions, differentiation and pathology. This volume should be of interest to cellular, molecular and developmental biologists, biochemists, biomedical researchers and pathophysiologists.
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Product details

  • Hardback | 448 pages
  • 158.75 x 230 x 25.4mm | 803g
  • Academic Press Inc
  • San Diego, United States
  • English
  • chapter references, subject index
  • 0125931654
  • 9780125931656

Table of contents

Part 1 Organization and definition of the basement membrane: collagen and basement membranes - discovery and progress, G.R. Martin and K.A. Piez; supra-molecular organization of basement membranes, P.D. Yurchenco and J. O'Rear; dermal-epidermal adhesion in skin, R.E. Burgeson; basement membrane molecules in vertebrate nervous system, J.R. Sanes; glomerular basement membrane - biology and physiology, B.S. Kasinath and Y.S. Kanwar; role of water of hydration in filtration function of proteoglycans of basement membrane, C.L. Haskin, et al. Part 2 Basement membrane components, biochemical nature, molecular structure and gene regulation: genes and regulation of basement membrane collagen and laminin synthesis, Y. Yamads and K. Kuhn; structure and function of laminin, J. Engel; laminin and collagen IV variants and heterogeneity in basement membrane composition, M. Paulsson; proteoglycans of basement membranes, D.M. Noonan and J.R. Hassell; other basement membrane proteins and their calcium-binding potential, R. Timpl and M. Aumailley. Part 3 Effect of cellular interactions with basement membranes: integrin structure and ligand specificity in cell-matrix interactions, R.H. Kramer, et al. proteoglycans of plasma membranes - multiple functions in cell surface biology, A.C. Rapraeger; peptide sequences in matrix proteins recognized by adhesion receptors, M.J. Humphries; role of basement membrane in differentiation, H.K. Kleinman, et al; extracellular matrix-bound growth factors, enzymes and plasma proteins, I. Vlodavsky, et al; role of extracellular matrix in cell migration and invasion, S.L. Goodman; basement membranes in development, P. Ekblom; molecular aspects of basement membrane pathology, D.H. Rohrbach and V.A. Murrah; Alport Syndrome and other inherited basement membrane disorders, K. Tryggvason, et al.
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